Association between Omentin-1 and Coronary Artery Disease: Pathogenesis and Clinical Research

被引：29

作者：

Askin, Lutfu ^{[1
]}

Duman, Hakan ^{[2
]}

Ozyildiz, Ali ^{[2
]}

Tanriverdi, Okan ^{[1
]}

Turkmen, Serdar ^{[1
]}

机构：

[1] Adiyaman Educ & Res Hosp, Dept Cardiol, Adiyaman, Turkey

[2] Recep Tayyip Erdogan Univ, Dept Cardiol, Med Fac, Rize, Turkey

来源：

CURRENT CARDIOLOGY REVIEWS | 2020年 / 16卷 / 03期

关键词：

Acute coronary syndrome; coronary artery disease; omentin-1; vascular smooth muscle cell; adipokines; adipose tissues; EPICARDIAL ADIPOSE-TISSUE; HIGH PLASMA OMENTIN; SERUM OMENTIN-1; RISK-FACTOR; ADIPOCYTOKINES; ISCHEMIA; ATRIAL; GENE;

D O I：

10.2174/1573403X16666200511085304

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Like other adipokines, omentin-1 is secreted from visceral adipose tissue and plays a vital role in the development of chronic inflammatory diseases, including cardiovascular events. Recent studies have shown that circulating omentin-1 levels are associated with various metabolic risk factors, such as high blood pressure, increased waist circumference, dyslipidemia, and glucose intolerance. The decrease in serum omentin level is an independent predictor of Coronary Artery Disease (CAD) and is associated with the severity of this disease. Since there is no relevant review in the literature, we aimed to summarize the studies on the relationship between omentin-1 and CAD.

引用

页码：198 / 201

页数：4

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