Synthesis of indolizidines from dialkylated isocyanides: a novel radical cyclisation/N-alkylation/ring closing metathesis approach

被引：18

作者：

Lamberto, Massimiliano ^{[1
,2
]}

Kilburn, Jeremy D. ^{[1
]}

机构：

[1] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England

[2] Monmouth Univ, Dept Chem Med Technol & Phys, W Long Branch, NJ 07764 USA

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 44期

关键词：

D O I：

10.1016/j.tetlet.2008.08.088

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two dialkylated isocyanides were first synthesised from simple starting materials and then used as building blocks for the synthesis of indolizidines via a novel radical cyclisation/N-alkylation/ring closing metathesis strategy. Several functionalised indolizidines were accessed in good to excellent yields. (c) 2008 Elsevier Ltd. All Fights reserved.

引用

页码：6364 / 6367

页数：4

共 19 条

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