Subsequential telomerase activity in exfoliated urinary cells detects recurrent disease in bladder cancer after transurethral resection

被引：0
|
作者：
Kitsukawa, SI
Ohyashiki, K
Yahata, N
Ebihara, Y
Aizawa, T
Ito, T
Miki, M
机构：
[1] Tokyo Med Univ, Dept Urol, Shinjuku Ku, Tokyo 1600023, Japan
[2] Tokyo Med Univ, Dept Internal Med 1, Shinjuku Ku, Tokyo 1600023, Japan
[3] Tokyo Med Univ, Dept Pathol 2, Shinjuku Ku, Tokyo 1600023, Japan
来源：
INTERNATIONAL JOURNAL OF ONCOLOGY | 1999年 / 15卷 / 03期
关键词：
telomerase; bladder neoplasms; transurethral resection; urine;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We assessed urinary telomerase activity in bladder cancer patients to provide additional information for monitoring after transurethral resection (TUR). Urinary telomerase activity was detected in 22/26 (84.6%) patients with known bladder tumor before TUR. Ten of 11 patients who were available for sequential follow-up examination had urinary telomerase activity before TUR. In 4 of the 10 patients, urinary telomerase activity disappeared following TUR with or without adjuvant intravesical therapy. Three of the remaining 6 patients had recurrent bladder tumors within three months after TUR. Urinary telomerase activity analysis from patients after TUR provides important information on microscopic recurrent bladder cancer.
引用
收藏
页码：505 / 510
页数：6
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