Subsequential telomerase activity in exfoliated urinary cells detects recurrent disease in bladder cancer after transurethral resection

被引：0

作者：

Kitsukawa, SI

Ohyashiki, K

Yahata, N

Ebihara, Y

Aizawa, T

Ito, T

Miki, M

机构：

[1] Tokyo Med Univ, Dept Urol, Shinjuku Ku, Tokyo 1600023, Japan

[2] Tokyo Med Univ, Dept Internal Med 1, Shinjuku Ku, Tokyo 1600023, Japan

[3] Tokyo Med Univ, Dept Pathol 2, Shinjuku Ku, Tokyo 1600023, Japan

来源：

INTERNATIONAL JOURNAL OF ONCOLOGY | 1999年 / 15卷 / 03期

关键词：

telomerase; bladder neoplasms; transurethral resection; urine;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We assessed urinary telomerase activity in bladder cancer patients to provide additional information for monitoring after transurethral resection (TUR). Urinary telomerase activity was detected in 22/26 (84.6%) patients with known bladder tumor before TUR. Ten of 11 patients who were available for sequential follow-up examination had urinary telomerase activity before TUR. In 4 of the 10 patients, urinary telomerase activity disappeared following TUR with or without adjuvant intravesical therapy. Three of the remaining 6 patients had recurrent bladder tumors within three months after TUR. Urinary telomerase activity analysis from patients after TUR provides important information on microscopic recurrent bladder cancer.

引用

页码：505 / 510

页数：6

共 33 条

[1] TELOMERASES [J].