Leonurus cardiaca L. as a Source of Bioactive Compounds: An Update of the European Medicines Agency Assessment Report (2010)

被引:17
作者
Fierascu, Radu Claudiu [1 ,2 ]
Fierascu, Irina [1 ,2 ]
Ortan, Alina [1 ]
Fierascu, Ioana Catalina [3 ]
Anuta, Valentina [3 ]
Velescu, Bruno Stefan [3 ]
Pituru, Silviu Mirel [3 ]
Dinu-Pirvu, Cristina Elena [1 ,3 ]
机构
[1] Univ Agron Sci & Vet Med Bucharest, 59 Marasti Blvd, Bucharest 011464, Romania
[2] ICECHIM Bucharest, Natl Inst Res & Dev Chem & Petrochem, 202 Spl Independentei, Bucharest 060021, Romania
[3] Univ Med & Pharm Carol Davila, 37 Dionisie Lupu Str, Bucharest 030167, Romania
关键词
ANTIOXIDANT ACTIVITY; EXTRACTS;
D O I
10.1155/2019/4303215
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Leonurus cardiaca L. (motherwort) is a perennial herb, native to Asia and southeastern Europe, with widespread global occurrence in present days. The plant was historically used as cardiotonic and for treating gynaecological afflictions (such as amenorrhea, dysmenorrhea, menopausal anxiety, or postpartum depression). Although its use in oriental and occidental medicine is relatively well documented, the recent progress registered raises the need for an update of the Medicines Agency assessment report on Leonurus cardiaca L., herba (2010). The current study presents the progress made within the 2010-2018 timeframe regarding the potential applications and scientific evidences supporting the traditional use of motherwort, in the same time suggesting future research opportunities.
引用
收藏
页数:13
相关论文
共 77 条
[1]   Epilepsy in the Renaissance: A survey of remedies from 16th and 17th century German herbals [J].
Adams, Michael ;
Schneider, Sarah-Vanessa ;
Kluge, Martin ;
Kessler, Michael ;
Hamburger, Matthias .
JOURNAL OF ETHNOPHARMACOLOGY, 2012, 143 (01) :1-13
[2]  
Anadon A., 2016, Nutraceuticals: Efficacy, Safety and Toxicity, P855, DOI 10.1016/B978-0-12-8021477.-
[3]  
[Anonymous], 2016, PRESCRIBER, DOI DOI 10.1002/PSB.1496
[4]  
ARMATU A, 2002, ROMANIA, V15, P5274
[5]  
Azimova Sh.S., 2012, Lipids, lipophilic components and essential oil from plant sources, V1, DOI [10.1007/978-0-85729-323-7, DOI 10.1007/978-0-85729-323-7]
[6]   The Effect of Leonurus cardiaca Herb Extract and Some of its Flavonoids on Mitochondrial Oxidative Phosphorylation in the Heart [J].
Bernatoniene, Jurga ;
Kopustinskiene, Dalia M. ;
Jakstas, Valdas ;
Majiene, Daiva ;
Baniene, Rasa ;
Kursvietiene, Lolita ;
Masteikova, Ruta ;
Savickas, Arunas ;
Toleikis, Adolfas ;
Trumbeckaite, Sonata .
PLANTA MEDICA, 2014, 80 (07) :525-532
[7]  
BIANCHI I, 2017, INTEGRATIVE CARDIOLO, V3, P18, DOI DOI 10.1007/978-3-319-40010-5
[8]  
Bojor O., 2003, GHIDUL PLANTELOR MED, P94
[9]   Review of Complementary and Alternative Medical Treatment of Arrhythmias [J].
Brenyo, Andrew ;
Aktas, Mehmet K. .
AMERICAN JOURNAL OF CARDIOLOGY, 2014, 113 (05) :897-903
[10]   Leonurine ameliorates kidney fibrosis via suppressing TGF-β and NF-κB signaling pathway in UUO mice [J].
Cheng, Haibo ;
Bo, Yun ;
Shen, Weixing ;
Tan, Jiani ;
Jia, Zhirong ;
Xu, Changliang ;
Li, Furong .
INTERNATIONAL IMMUNOPHARMACOLOGY, 2015, 25 (02) :406-415