Regulation of Metabolism: A Cross Talk Between Gut Microbiota and Its Human Host

被引：43

作者：

Burcelin, Remy ^{[1
]}

机构：

[1] Fac Med Toulouse, INSERM, Inst Malad Metabol & Cardiovasc, F-31073 Toulouse, France

来源：

PHYSIOLOGY | 2012年 / 27卷 / 05期

关键词：

HIGH-FAT-DIET; INSULIN-RESISTANCE; INTESTINAL MICROBIOTA; INDUCED OBESITY; ADIPOSE-TISSUE; T-CELLS; INFLAMMATION; MICE; ENDOTOXEMIA; MECHANISMS;

D O I：

10.1152/physiol.00023.2012

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The recent epidemic of obesity and diabetes and the diversity at the individual level could be explained by the intestinal microbiota-to-host relationship. More than four million gene products from the microbiome could interact with the immune system to induce a tissue metabolic infection, which is the molecular origin of the low-grade inflammation that characterizes the onset of obesity and diabetes.

引用

页码：300 / 307

页数：8

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