Parasite glycoconjugates.: Part 9.: Synthesis of dec-9-enyl β-D-galactopyranosyl-(1→4)-α-D-mannopyranosyl phosphate and its epimers at the D-galactose moiety, substrate analogues for the elongating α-D-mannopyranosylphosphate transferase in the Leishmania

被引：25

作者：

Ivanova, IA

Ross, AJ

Ferguson, MAJ

Nikolaev, AV ^{[1
]}

机构：

[1] Univ Dundee, Dept Chem, Dundee DD1 4HN, Scotland

[2] Univ Dundee, Dept Biochem, Dundee DD1 4HN, Scotland

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 12期

关键词：

D O I：

10.1039/a900375d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A set of phosphodisaccharides, substrate analogues, which will be used to study the acceptor substrate specificity of the Leishmania biosynthetic enzymes, have been synthesized using the trichloroacetimidate method for the glycosylation reactions, S(N)2 nucleophilic displacement of triflic esters for epimerization and the glycosyl hydrogenphosphonate method for phosphorylation.

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页码：1743 / 1753

页数：11

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