Very Late Isolated CNS Relapse of Acute Myeloid Leukemia

被引：3
作者：
Molina, Blanca [1 ]
Lassaletta, Alvaro [1 ]
Gonzalez-Vicent, Marta [1 ]
Andion, Maitane [1 ]
Diaz, Miguel A. [1 ]
Madero, Luis [1 ]
机构：
[1] Hosp Nino Jesus, Pediat Hematol Oncol Dept, Madrid 28009, Spain
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2013年 / 35卷 / 02期
关键词：
late relapse; isolated; CNS; AML; children; STEM-CELL TRANSPLANTATION; NERVOUS-SYSTEM RELAPSE; ACUTE MYELOGENOUS LEUKEMIA; PROGNOSTIC-FACTORS; CD56; EXPRESSION; CHILDREN; THERAPY; ABNORMALITIES; MULTICENTER; DIAGNOSIS;
D O I：
10.1097/MPH.0b013e318281e63b
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Isolated central nervous system (CNS) relapse in acute myeloid leukemia (AML) rarely occurs later than 2 years after remission. We present a child diagnosed with AML (FAB M5) without CNS involvement at diagnosis who was treated with chemotherapy and consolidated with autologous hematopoietic stem cell transplantation. He was in complete remission for > 6 years until he had an isolated CNS relapse. He was treated with only intrathecal chemotherapy and achieved a second complete remission, but relapsed in the bone marrow 5 months after the CNS relapse. Treatment of late isolated CNS relapse of AML is discussed.
引用
收藏
页码：E57 / E59
页数：3
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