Lung and Heart Allocation in the United States

被引:101
作者
Colvin-Adams, M. [1 ,2 ]
Valapour, M. [1 ,3 ]
Hertz, M. [1 ,3 ]
Heubner, B. [1 ]
Paulson, K. [3 ]
Dhungel, V. [2 ]
Skeans, M. A. [1 ]
Edwards, L. [4 ]
Ghimire, V. [4 ]
Waller, C. [4 ]
Cherikh, W. S. [4 ]
Kasiske, B. L. [1 ,5 ]
Snyder, J. J. [1 ,6 ]
Israni, A. K. [1 ,5 ,6 ]
机构
[1] Minneapolis Med Res Fdn Inc, Sci Registry Transplant Recipients, Minneapolis, MN USA
[2] Univ Minnesota, Dept Med, Div Cardiol, Minneapolis, MN 55455 USA
[3] Univ Minnesota, Dept Med, Div Pulm & Crit Care Med, Minneapolis, MN 55455 USA
[4] United Network Organ Sharing, Richmond, VA USA
[5] Univ Minnesota, Hennepin Cty Med Ctr, Dept Med, Minneapolis, MN 55415 USA
[6] Univ Minnesota, Dept Epidemiol & Community Hlth, Minneapolis, MN USA
关键词
Heart allograft; lung allograft; organ allocation; transplant waiting list; transplantation; VENTRICULAR ASSIST DEVICE; PEDIATRIC TRANSPLANTATION; ORGAN-TRANSPLANTATION; PROCUREMENT; CANDIDATES; OUTCOMES; THERAPY; NETWORK; POLICY;
D O I
10.1111/j.1600-6143.2012.04258.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
Lung and heart allocation in the United States has evolved over the past 2030 years to better serve transplant candidates and improve organ utilization. The current lung allocation policy, based on the Lung Allocation Score, attempts to take into account risk of death on the waiting list and chance of survival posttransplant. This policy is flexible and can be adjusted to improve the predictive ability of the score. Similarly, in response to the changing clinical phenotype of heart transplant candidates, heart allocation policies have evolved to a multitiered algorithm that attempts to prioritize organs to the most infirm, a designation that fluctuates with trends in therapy. The Organ Procurement and Transplantation Network and its committees have been responsive, as demonstrated by recent modifications to pediatric heart allocation and mechanical circulatory support policies and by ongoing efforts to ensure that heart allocation policies are equitable and current. Here we examine the development of US lung and heart allocation policy, evaluate the application of the current policy on clinical practice and explore future directions for lung and heart allocation.
引用
收藏
页码:3213 / 3234
页数:22
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