Use of thiazolidinedione and cancer risk in Type 2 diabetes: The Hong Kong diabetes registry

被引：10
|
作者：
Yang, Xilin [1 ,2 ]
So, Wing-Yee [2 ,3 ,4 ]
Ma, Ronald C. W. [2 ,3 ,4 ]
Yu, Linda W. L. [5 ]
Kong, Alice P. S. [2 ,3 ,4 ]
Lee, Heung Man [2 ,3 ,4 ]
Xu, Gang [2 ,3 ,4 ]
Ozaki, Risa [2 ,3 ]
Ko, Gary T. C. [2 ,3 ]
Chan, Juliana C. N. [2 ,3 ,4 ]
机构：
[1] Tianjin Med Univ, Coll Publ Hlth, Dept Epidemiol, Tianjin 300070, Peoples R China
[2] Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China
[3] Chinese Univ Hong Kong, Hong Kong Inst Diabet & Obes, Hong Kong, Hong Kong, Peoples R China
[4] Chinese Univ Hong Kong, Li Ka Shing Inst Hlth Sci, Hong Kong, Hong Kong, Peoples R China
[5] Hosp Author Headquarter, Hong Kong, Hong Kong, Peoples R China
来源：
DIABETES RESEARCH AND CLINICAL PRACTICE | 2012年 / 97卷 / 01期
关键词：
Thiazolidinediones; Cancer; Type; 2; diabetes; ROSIGLITAZONE; HYPERGLYCEMIA; PIOGLITAZONE; ASSOCIATIONS;
D O I：
10.1016/j.diabres.2012.03.006
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We examined possible anticancer effects of thiazolidinediones (TZDs) in 6074 Chinese with Type 2 diabetes free of cancer at enrolment. During a median follow-up of 4.93 years, 270 patients developed cancer. Use of TZDs was associated with reduced risk of cancer in a dose-response manner in multivariable analysis. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：E11 / E15
页数：5
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