Synthesis of the Gd(III) complex with a tetrazole-armed macrocyclic ligand as a potential MRI contrast agent

被引:22
|
作者
Aime, S
Cravotto, G
Crich, SG
Giovenzana, GB
Ferrari, M
Palmisano, G
Sisti, M
机构
[1] IFM, Dipartimento Chim, I-10125 Turin, Italy
[2] Dipartimento Sci & Technol Farmaco, I-10125 Turin, Italy
[3] Dipartimento Sci Chim Alimentari Farmaceut & Farm, I-28100 Novara, Italy
[4] Univ Milan, Dipartimento Chim Organ & Ind, I-20133 Milan, Italy
[5] Dipartimento Sci Chim Fis & Matemat, I-22100 Como, Italy
关键词
D O I
10.1016/S0040-4039(01)02272-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We report the synthesis and the properties of the Gd(III) complex with 4 (H(4)dotetra), a novel mixed pendant-arm macrocyclic ligand embodying a tetrazole subunit in a N5O3 donor set as a potential magnetic resonance imaging (MRI) contrast agent. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:783 / 786
页数:4
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