Spatially filtered magnetoencephalography compared with electrocorticography to identify intrinsically epileptogenic focal cortical dysplasia

被引:32
作者
Ishii, Ryouhei [2 ]
Canuet, Leonides [2 ,3 ]
Ochi, Ayako [1 ]
Xiang, Jing [4 ]
Imai, Katsumi [1 ]
Chan, Derrick [1 ]
Iwase, Masao [2 ]
Takeda, Masatoshi [2 ]
Snead, O. Carter, III [1 ]
Otsubo, Hiroshi [1 ]
机构
[1] Univ Toronto, Hosp Sick Children, Dept Pediat, Div Neurol, Toronto, ON M5G 1X8, Canada
[2] Osaka Univ, Grad Sch Med, Dept Psychiat & Behav Prote, Osaka, Japan
[3] Prov Hosp Saturnino Lora, Dept Neurol, Santiago De Cuba, Cuba
[4] Univ Cincinnati, Cincinnati Childrens Hosp, Med Ctr, Dept Neurol, Cincinnati, OH 45221 USA
关键词
Epilepsy; Focal cortical dysplasia (FCD); Electrocorticography (ECoG); Magnetoencephalography (MEG); Synthetic Aperture Magnetometry-kurtosis (SAM(g(2)));
D O I
10.1016/j.eplepsyres.2008.06.006
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This study was carried out to evaluate Synthetic Aperture Magnetometry-kurtosis (SAM(g(2))), a spatially filtered source localization technique in magnetoencephalography (MEG), for identification of epileptogenic areas of focal cortical dysplasia (FCD). Three children with FCD were investigated to localize the ictal onset zone (IOZ). All patients subsequently had extra-operative electrocorticography (ECoG) for intractable epilepsy and surgical resection. SAM(g2) analysis showed overlapping of interictal MEG spike sources with the IOZ on ECoG in all children. We recommend MEG-SAM(g(2)) and MEG interictal spike source localization in patients with epileptogenic FCD. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:228 / 232
页数:5
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