Power and wavelength dependence of photoenhancement in (CdSe)ZnS-dopamine in aqueous solution and live cells

被引：6

作者：

Clarke, S. ^{[1
]}

Koshy, S. ^{[1
]}

Zhang, J. ^{[1
]}

Cohen, N. ^{[2
]}

Nadeau, J. ^{[1
]}

机构：

[1] McGill Univ, Dept Biomed Engn, Montreal, PQ H3A 2B4, Canada

[2] Univ Leeds, Sch Comp, Leeds LS2 9JT, W Yorkshire, England

来源：

ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL PHYSICS | 2008年 / 222卷 / 5-6期

基金：

英国工程与自然科学研究理事会;

关键词：

(CdSe)ZnS-dopamine; photoluminescence; photoenhancement; living cell;

D O I：

10.1524/zpch.2008.6012

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

CdSe(ZnS) quantum dots conjugated to the electron donor dopamine show enhancement of photoluminescence over a time course of seconds to minutes when exposed to ultraviolet or blue irradiation. This phenomenon is observed when the dots are in aqueous solution as well its after endocytosis by living cells. The rate of enhancement is directly related to the number of dopamine conjugates per quantum dot, and can be semi-quantitatively adjusted over it wide range. Uptake of the particles by cells is also dependent upon surface coverage, with moderate coverages proving ideal for both uptake and relative signal enhancement. The enhancement is strongly power-dependent and may also show dependence upon wavelength; however. direct excitation of the dopamine molecule is not necessary for the enhancement effect.

引用

页码：851 / 863

页数：13

共 25 条

[1] Photochemical instability of CdSe nanocrystals coated by hydrophilic thiols [J].

Aldana, J ;

Wang, YA ;

Peng, XG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (36) :8844-8850

[2] Surface state analysis of photobrightening in CdSe nanocrystal thin films [J].

Asami, H ;

Abe, Y ;

Ohtsu, T ;

Kamiya, I ;

Hara, M .

JOURNAL OF PHYSICAL CHEMISTRY B, 2003, 107 (46) :12566-12568

[3] Role of free cadmium and selenium ions in the potential mechanism for the enhancement of photoluminescence of CdSe quantum dots under ultraviolet irradiation [J].

Bakalova, R ;

Zhelev, Z ;

Jose, R ;

Nagase, T ;

Ohba, H ;

Ishikawa, M ;

Baba, Y .

JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2005, 5 (06) :887-894

[4]

Barreto WJ, 1999, SPECTROCHIM ACTA A, V55, P65

[5] Two-photon-induced photoenhancement of densely packed CdSe/ZnSe/ZnS nanocrystal solids and its application to multilayer optical data storage [J].

Chon, JWM ;

Zijlstra, P ;

Gu, M ;

van Embden, J ;

Mulvaney, P .

APPLIED PHYSICS LETTERS, 2004, 85 (23) :5514-5516

[6] Effect of ligand density on the spectral, physical, and biological characteristics of CdSe/ZnS quantum dots [J].

Clarke, Samuel J. ;

Hollmann, C. A. ;

Aldaye, Faisal A. ;

Nadeau, Jay L. .

BIOCONJUGATE CHEMISTRY, 2008, 19 (02) :562-568

[7]

CLARKE SJ, 2006, NAT MAT

[8] Photo-activated luminescence of CdSe quantum dot monolayers [J].

Cordero, SR ;

Carson, PJ ;

Estabrook, RA ;

Strouse, GF ;

Buratto, SK .

JOURNAL OF PHYSICAL CHEMISTRY B, 2000, 104 (51) :12137-12142

[9] Tracking individual proteins in living cells using single quantum dot imaging [J].

Courty, Sebastien ;

Bouzigues, Cedric ;

Luccardini, Camilla ;

Ehrensperger, Marie-Virginie ;

Bonneau, Stephane ;

Dahan, Maxime .

MEASURING BIOLOGICAL RESPONSES WITH AUTOMATED MICROSCOPY, 2006, 414 :211-228

[10] Probing biocatalytic transformations with CdSe-ZnS QDs [J].

Gill, Ron ;

Freeman, Ronit ;

Xu, Jian-Ping ;

Willner, Itamar ;

Winograd, Shira ;

Shweky, Itzik ;

Banin, Uri .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (48) :15376-15377

← 1 2 3 →