Electrocardiographic changes associated with dehydration in rabbits (Oryctolagus cuniculus)

A study was conducted on twelve healthy and clinically normal New Zealand White rabbits of either sex, weighing between 2-3 kg and aged between 1-2 years to observe the electrocardiographic changes during induced dehydration. Progressive dehydration till about 10% body weight loss was monitored that reflected in increased haematocrit and serum potassium levels. Increase in heart rate was seen with progressive water deprivation. Electrocardiographic changes observed were reflective of those associated with hyperkalaemia and include a significant increase in QRS complex and T wave amplitude along with an increase in the duration of all the waves. These characteristic changes were fairly indicative of the hydration status, more precisely on the electrolyte balance that can be assessed for an early recognition and clinical intervention.