Antiviral Potential of Algae Polysaccharides Isolated from Marine Sources: A Review

被引:190
作者
Ahmadi, Azin [1 ]
Moghadamtousi, Soheil Zorofchian [2 ]
Abubakar, Sazaly [1 ]
Zandi, Keivan [1 ,3 ]
机构
[1] Univ Malaya, Fac Med, TIDREC, Dept Med Microbiol, Kuala Lumpur 50603, Malaysia
[2] Univ Malaya, Fac Sci, Inst Biol Sci, Biochem Program, Kuala Lumpur 50603, Malaysia
[3] Bushehr Univ Med Sci, Persian Gulf Marine Biotechnol Res Ctr, Bushehr 7514633341, Iran
关键词
HUMAN-IMMUNODEFICIENCY-VIRUS; HERPES-SIMPLEX; SULFATED POLYSACCHARIDES; UNDARIA-PINNATIFIDA; SEAWEED POLYSACCHARIDES; BIOLOGICAL-ACTIVITIES; STRUCTURAL-ANALYSIS; BROWN-ALGAE; RED; FUCOIDAN;
D O I
10.1155/2015/825203
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
From food to fertilizer, algal derived products are largely employed in assorted industries, including agricultural, biomedical, food, and pharmaceutical industries. Among different chemical compositions isolated from algae, polysaccharides are the most well established compounds, which were subjected to a variety of studies due to extensive bioactivities. Over the past few decades, the promising results for antiviral potential of algae-derived polysaccharides have advocated them as inordinate candidates for pharmaceutical research. Numerous studies have isolated various algal polysaccharides possessing antiviral activities, including carrageenan, alginate, fucan, laminaran, and naviculan. In addition, different mechanisms of action have been reported for these polysaccharides, such as inhibiting the binding or internalization of virus into the host cells or suppressing DNA replication and protein synthesis. This review strives for compiling previous antiviral studies of algae-derived polysaccharides and their mechanism of action towards their development as natural antiviral agents for future investigations.
引用
收藏
页数:10
相关论文
共 99 条
  • [21] INHIBITION OF HERPESVIRUS REPLICATION BY MARINE ALGAE EXTRACTS
    DEIG, EF
    EHRESMANN, DW
    HATCH, MT
    RIEDLINGER, DJ
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1974, 6 (04) : 524 - 525
  • [22] Galactans: An Overview of their Most Important Sourcing and Applications as Natural Polysaccharides
    Delattre, Cedric
    Fenoradosoa, Taratra Andree
    Michaud, Philippe
    [J]. BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY, 2011, 54 (06) : 1075 - 1092
  • [23] A NEW APPROACH FOR THE CHARACTERIZATION OF POLYSACCHARIDES FROM ALGAE - PRESENCE OF 4 MAIN ACIDIC POLYSACCHARIDES IN 3 SPECIES OF THE CLASS PHAEOPHYCEA
    DIETRICH, CP
    FARIAS, GGM
    DEABREU, LRD
    LEITE, EL
    DASILVA, LF
    NADER, HB
    [J]. PLANT SCIENCE, 1995, 108 (02) : 143 - 153
  • [24] ANTIVIRAL SUBSTANCES FROM CALIFORNIA MARINE-ALGAE
    EHRESMANN, DW
    DEIG, EF
    HATCH, MT
    DISALVO, LH
    VEDROS, NA
    [J]. JOURNAL OF PHYCOLOGY, 1977, 13 (01) : 37 - 40
  • [25] In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus
    Elizondo-Gonzalez, Regina
    Elizabeth Cruz-Suarez, L.
    Ricque-Marie, Denis
    Mendoza-Gamboa, Edgar
    Rodriguez-Padilla, Cristina
    Trejo-Avila, Laura M.
    [J]. VIROLOGY JOURNAL, 2012, 9
  • [26] Antimicrobial effect of phlorotannins from marine brown algae
    Eom, Sung-Hwan
    Kim, Young-Mog
    Kim, Se-Kwon
    [J]. FOOD AND CHEMICAL TOXICOLOGY, 2012, 50 (09) : 3251 - 3255
  • [27] DL-galactan hybrids and agarans from gametophytes of the red seaweed Gymnogongrus torulosus
    Estevez, JM
    Ciancia, M
    Cerezo, AS
    [J]. CARBOHYDRATE RESEARCH, 2001, 331 (01) : 27 - 41
  • [28] The potential molecular targets of marine sulfated polymannuroguluronate interfering with HIV-1 entry - Interaction between SPMG and HIV-1 rgp120 and CD4 molecule
    Geng, MY
    Li, FC
    Xin, XL
    Li, J
    Yan, ZW
    Guan, HS
    [J]. ANTIVIRAL RESEARCH, 2003, 59 (02) : 127 - 135
  • [29] GERBER P, 1958, P SOC EXP BIOL MED, V99, P590, DOI 10.3181/00379727-99-24429
  • [30] Heterofucans from the Brown Seaweed Canistrocarpus cervicornis with Anticoagulant and Antioxidant Activities
    Gomes Camara, Rafael Barros
    Costa, Leandro Silva
    Fidelis, Gabriel Pereira
    Duarte Barreto Nobre, Leonardo Thiago
    Dantas-Santos, Nednaldo
    Cordeiro, Sara Lima
    Santos Pereira Costa, Mariana Santana
    Alves, Luciana Guimaraes
    Oliveira Rocha, Hugo Alexandre
    [J]. MARINE DRUGS, 2011, 9 (01) : 124 - 138