Antiviral Potential of Algae Polysaccharides Isolated from Marine Sources: A Review

被引：190
作者：
Ahmadi, Azin [1 ]
Moghadamtousi, Soheil Zorofchian [2 ]
Abubakar, Sazaly [1 ]
Zandi, Keivan [1 ,3 ]
机构：
[1] Univ Malaya, Fac Med, TIDREC, Dept Med Microbiol, Kuala Lumpur 50603, Malaysia
[2] Univ Malaya, Fac Sci, Inst Biol Sci, Biochem Program, Kuala Lumpur 50603, Malaysia
[3] Bushehr Univ Med Sci, Persian Gulf Marine Biotechnol Res Ctr, Bushehr 7514633341, Iran
来源：
BIOMED RESEARCH INTERNATIONAL | 2015年 / 2015卷
关键词：
HUMAN-IMMUNODEFICIENCY-VIRUS; HERPES-SIMPLEX; SULFATED POLYSACCHARIDES; UNDARIA-PINNATIFIDA; SEAWEED POLYSACCHARIDES; BIOLOGICAL-ACTIVITIES; STRUCTURAL-ANALYSIS; BROWN-ALGAE; RED; FUCOIDAN;
D O I：
10.1155/2015/825203
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
From food to fertilizer, algal derived products are largely employed in assorted industries, including agricultural, biomedical, food, and pharmaceutical industries. Among different chemical compositions isolated from algae, polysaccharides are the most well established compounds, which were subjected to a variety of studies due to extensive bioactivities. Over the past few decades, the promising results for antiviral potential of algae-derived polysaccharides have advocated them as inordinate candidates for pharmaceutical research. Numerous studies have isolated various algal polysaccharides possessing antiviral activities, including carrageenan, alginate, fucan, laminaran, and naviculan. In addition, different mechanisms of action have been reported for these polysaccharides, such as inhibiting the binding or internalization of virus into the host cells or suppressing DNA replication and protein synthesis. This review strives for compiling previous antiviral studies of algae-derived polysaccharides and their mechanism of action towards their development as natural antiviral agents for future investigations.
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