4-Alkylcoumarins and a phloroglucinol from the stem bark of Calophyllum gracilentum

被引:4
作者
Lim, Chan Kiang [1 ]
Ham, Yenn Pinn [1 ]
Lim, Li Qing [1 ]
Jong, Vivien Yi Mian [2 ]
机构
[1] Univ Tunku Abdul Rahman, Fac Sci, Dept Chem Sci, Kampar 31900, Perak, Malaysia
[2] Univ Teknol MARA, Fac Appl Sci, Ctr Appl Sci, Samarahan Campus 2,Jalan Meranek, Kota Samarahan 94300, Sarawak, Malaysia
关键词
Calophyllum gracilentum; Guttiferae; 4-Alkylcoumarin; Phloroglucinol; CHEMICAL-CONSTITUENTS; ACIDS;
D O I
10.1016/j.phytol.2019.01.022
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Three new 4-alkylcoumarins, gracilenins A-C (1-3) and a new phloroglucinol, gracilenol (4), along with two known compounds, euxanthone and friedelin were isolated from the stem bark of Calophyllum gracilentum. Their structures were established on the basis of 1D and 2D NMR spectroscopic data and HRESIMS analysis. This is the first report of 4-(butan-2-yl) coumarin derivatives in this genus.
引用
收藏
页码:99 / 102
页数:4
相关论文
共 11 条
  • [1] New chromanone acids with antibacterial activity from Calophyllum brasiliense
    Cottiglia, F
    Dhanapal, B
    Sticher, O
    Heilmann, J
    [J]. JOURNAL OF NATURAL PRODUCTS, 2004, 67 (04): : 537 - 541
  • [2] Composition of fatty acids triacylglycerols and unsaponifiable matter in Calophyllum calaba L. oil from Guadeloupe
    Crane, S
    Aurore, G
    Joseph, H
    Mouloungui, Z
    Bourgeois, P
    [J]. PHYTOCHEMISTRY, 2005, 66 (15) : 1825 - 1831
  • [3] A chromene acid from Calophyllum cordato-oblongum
    Dharmaratne, HRW
    Perera, DSC
    Marasinghe, GPK
    Jamie, J
    [J]. PHYTOCHEMISTRY, 1999, 51 (01) : 111 - 113
  • [4] Antimalarial xanthones from Calophyllum caledonicum and Garcinia viellardii
    Hay, AE
    Hélesbeux, JJ
    Duval, O
    Labaïed, M
    Grellier, P
    Richomme, P
    [J]. LIFE SCIENCES, 2004, 75 (25) : 3077 - 3085
  • [5] Anti-tumor-promoting effects of 8-substituted 7-methoxycoumarins on Epstein-Barr virus activation assay
    Ito, C
    Itoigawa, M
    Furukawa, H
    Tokuda, H
    Okuda, Y
    Mukainaka, T
    Okuda, M
    Nishino, H
    [J]. CANCER LETTERS, 1999, 138 (1-2) : 87 - 92
  • [6] Chemical constituents of Calophyllum brasiliensis:: Structure elucidation of seven new xanthones and their cancer chemopreventive activity
    Ito, C
    Itoigawa, M
    Mishina, Y
    Cechinel, V
    Mukainaka, T
    Tokuda, H
    Nishino, H
    Furukawa, H
    [J]. JOURNAL OF NATURAL PRODUCTS, 2002, 65 (03): : 267 - 272
  • [7] Antimicrobial activity of Calophyllum soulattri
    Khan, MR
    Kihara, M
    Omoloso, AD
    [J]. FITOTERAPIA, 2002, 73 (7-8) : 741 - 743
  • [8] In vitro cytotoxic activity of isolated compounds from Malaysian Calophyllum species
    Lim, Chan Kiang
    Hemaroopini, Subramaniam
    Gan, Shu Ying
    Loo, Siew Mian
    Low, Jo Ring
    Jong, Vivien Yi Mian
    Soo, Hsien Chuen
    Leong, Chee Onn
    Mai, Chun Wai
    Chee, Chin Fei
    [J]. MEDICINAL CHEMISTRY RESEARCH, 2016, 25 (08) : 1686 - 1694
  • [9] Cytotoxic effects of mammea type coumarins from Calophyllum brasiliense
    Reyes-Chilpa, R
    Estrada-Muñiz, E
    Apan, TR
    Amekraz, B
    Aumelas, A
    Jankowski, CK
    Vázquez-Torres, M
    [J]. LIFE SCIENCES, 2004, 75 (13) : 1635 - 1647
  • [10] Gastroprotective effect from Calophyllum brasiliense Camb. bark on experimental gastric lesions in rats and mice
    Sartori, NT
    Canepelle, D
    de Sousa, PT
    Martins, DTO
    [J]. JOURNAL OF ETHNOPHARMACOLOGY, 1999, 67 (02) : 149 - 156