Current Treatment Options for Peripheral Nerve Hyperexcitability Syndromes

被引：7
作者：
Elangovan, Cheran [1 ]
Morawo, Adeolu [1 ]
Ahmed, Aiesha [1 ]
机构：
[1] Penn State Univ, Dept Neurol, 30 Hope Dr,EC 037, Hershey, PA 17033 USA
来源：
CURRENT TREATMENT OPTIONS IN NEUROLOGY | 2018年 / 20卷 / 07期
关键词：
Hyperexcitability; Neuromyotonia; Autoimmunity; Paraneoplastic; Immunosuppression; NEUROMYOTONIA ISAACS SYNDROME; CRAMP-FASCICULATION SYNDROME; POTASSIUM CHANNEL ANTIBODY; MUSCLE-FIBER ACTIVITY; MORVANS-SYNDROME; ACQUIRED NEUROMYOTONIA; MYASTHENIA-GRAVIS; LIMBIC ENCEPHALITIS; NEUROPATHIC PAIN; THERAPIES;
D O I：
10.1007/s11940-018-0510-9
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Purpose of review Peripheral nerve hyperexcitability (PNH) syndromes are divided into primary and secondary groups based on the presence or absence of demonstrable peripheral nerve disease. In this review, we systematically evaluate the evidence for current therapies and supportive managements based on autoimmune, paraneoplastic, and genetic components in pathophysiology reported in the literature. Recent findings Current therapy options are based on symptomatic management as well as focusing the underlying immune/genetic/paraneoplastic pathology by immunosuppressants, chemotherapy, and surgery. Summary Further research is desired to provide treatment options geared specifically towards addressing PNH. Supportive care can also be an area for future research.
引用
收藏
页数：14
相关论文
共 50 条
  • [31] Current Treatment Options for HIV Elite Controllers: a Review
    Promer, Katherine
    Karris, Maile Y.
    CURRENT TREATMENT OPTIONS IN INFECTIOUS DISEASES, 2018, 10 (02) : 302 - 309
  • [32] Use of paper for treatment of a peripheral nerve trauma in the rat
    Kauppila, T
    Jyvasjarvi, E
    Murtomaki, S
    Mansikka, H
    Pertovaara, A
    Virtanen, I
    Liesi, P
    NEUROREPORT, 1997, 8 (14) : 3151 - 3155
  • [33] Muscle-Specific Tyrosine Kinase Antibody Positive Myasthenia Gravis With Peripheral Nerve Hyperexcitability: Case Report and Literature Review
    Yang, Li
    CLINICAL NEUROPHARMACOLOGY, 2021, 44 (02) : 57 - 61
  • [34] An overview of the non-procedural treatment options for peripheral neuropathic pain
    Zeldin, Evan R.
    Goddard, Adam R.
    Boyle, Maxwell S.
    Madathil, Renee L.
    Rosenvall, Erick
    Majithia, Kajri A.
    Morrison, Eric J.
    MUSCLE & NERVE, 2024, : 791 - 801
  • [35] Progressive multifocal leukoencephalopathy: current treatment options and future perspectives
    Pavlovic, Dejan
    Patera, Andriani C.
    Nyberg, Fredrik
    Gerber, Marianne
    Liu, Maggie
    THERAPEUTIC ADVANCES IN NEUROLOGICAL DISORDERS, 2015, 8 (06) : 255 - 273
  • [36] Current and emerging treatment options for Wiskott-Aldrich syndrome
    Worth, Austen J. J.
    Thrasher, Adrian J.
    EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2015, 11 (09) : 1015 - 1032
  • [37] An overview of current and future treatment options for patients with cytomegalovirus retinitis
    Dunn, James P.
    EXPERT OPINION ON ORPHAN DRUGS, 2014, 2 (10): : 999 - 1013
  • [38] Varicella zoster: an update on current treatment options and future perspectives
    Kim, Sharon R.
    Khan, Farhan
    Tyring, Stephen K.
    EXPERT OPINION ON PHARMACOTHERAPY, 2014, 15 (01) : 61 - 71
  • [39] Post burn pruritus-A review of current treatment options
    Zachariah, Jewel Raj
    Rao, Aravind Lakshmana
    Prabha, Ratna
    Gupta, Ashish Kumar
    Paul, M. Kingsly
    Lamba, Shashank
    BURNS, 2012, 38 (05) : 621 - 629
  • [40] Peripheral and central hyperexcitability: Differential signs and symptoms in persistent pain
    Coderre, TJ
    Katz, J
    BEHAVIORAL AND BRAIN SCIENCES, 1997, 20 (03) : 404 - +
12345