Current Treatment Options for Peripheral Nerve Hyperexcitability Syndromes

被引：7
|
作者：
Elangovan, Cheran [1 ]
Morawo, Adeolu [1 ]
Ahmed, Aiesha [1 ]
机构：
[1] Penn State Univ, Dept Neurol, 30 Hope Dr,EC 037, Hershey, PA 17033 USA
来源：
CURRENT TREATMENT OPTIONS IN NEUROLOGY | 2018年 / 20卷 / 07期
关键词：
Hyperexcitability; Neuromyotonia; Autoimmunity; Paraneoplastic; Immunosuppression; NEUROMYOTONIA ISAACS SYNDROME; CRAMP-FASCICULATION SYNDROME; POTASSIUM CHANNEL ANTIBODY; MUSCLE-FIBER ACTIVITY; MORVANS-SYNDROME; ACQUIRED NEUROMYOTONIA; MYASTHENIA-GRAVIS; LIMBIC ENCEPHALITIS; NEUROPATHIC PAIN; THERAPIES;
D O I：
10.1007/s11940-018-0510-9
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Purpose of review Peripheral nerve hyperexcitability (PNH) syndromes are divided into primary and secondary groups based on the presence or absence of demonstrable peripheral nerve disease. In this review, we systematically evaluate the evidence for current therapies and supportive managements based on autoimmune, paraneoplastic, and genetic components in pathophysiology reported in the literature. Recent findings Current therapy options are based on symptomatic management as well as focusing the underlying immune/genetic/paraneoplastic pathology by immunosuppressants, chemotherapy, and surgery. Summary Further research is desired to provide treatment options geared specifically towards addressing PNH. Supportive care can also be an area for future research.
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页数：14
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