Porphyra-334, a potential natural source for UVA protective sunscreens

被引:82
作者
Torres, A
Enk, CD
Hochberg, M
Srebnik, M
机构
[1] Hebrew Univ Jerusalem, Sch Pharm, Dept Chem & Nat Prod, IL-91120 Jerusalem, Israel
[2] Hebrew Univ Jerusalem, Hadassah Med Ctr, Dept Dermatol, Jerusalem, Israel
关键词
D O I
10.1039/b517330m
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The mycosporine-like amino acid (MAA), porphyra-334 (lambda(max) = 334 nm; epsilon = 42 300 M-1 cm(-1)), was isolated from the aquatic cyanobacterium Aphanizomenon flos-aquae (AFA) and its structure was verified by spectroscopic methods. The UVA absorption properties of the crude methanolic extract were determined against two commercial sun care products in terms of mean critical wavelength, mean UVA/UVB ratios and UVA protection category (Boots the Chemists, Ltd.). The crude methanolic extract from AFA exhibited maximum UVA protection comparable to that determined for Boots SPF 4.
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页码:432 / 435
页数:4
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