Synthesis of (macro) heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions

被引：21
|
作者：
Barreto, Angelica de Fatima S. [1 ]
Andrade, Carlos Kleber Z. [1 ]
机构：
[1] Univ Brasilia, Inst Quim, Lab Quim Metodol & Organ Sintet LaQMOS, BR-70910970 Brasilia, DF, Brazil
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 15卷
关键词：
consecutive/repetitive multicomponent reactions; isocyanide; isocyanide-based multicomponent reactions; (macro) heterocycles; Passerini reaction; Ugi reaction; BIFUNCTIONAL BUILDING-BLOCKS; HYBRID MACROCYCLES; UGI; MACROCYCLIZATIONS; TETRAZOLES; CHEMISTRY; CAGES; MIBS;
D O I：
10.3762/bjoc.15.88
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the synthesis of structurally diverse heterocycles. These strategies have also allowed the synthesis of a plethora of macroheterocycles in a reduced number of steps.
引用
收藏
页码：906 / 930
页数：25
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