Biomedical Applications of Clay

被引:18
作者
Chrzanowski, Wojciech [1 ]
Kim, Sally Yunsun [1 ]
Abou Neel, Ensanya Ali [2 ,3 ,4 ]
机构
[1] Univ Sydney, Fac Pharm, Sydney, NSW 2006, Australia
[2] King Abdulaziz Univ, Conservat Dent Sci Dept, Div Biomat, Jeddah 22254, Saudi Arabia
[3] Tanta Univ, Fac Dent, Biomat Dept, Tanta 31111, Egypt
[4] UCL Eastman Dent Inst, Div Biomat & Tissue Engn, London WC1X 8LD, England
关键词
DRUG-RELEASE; SILICATE NANOCOMPOSITES; HYDROGELS; DELIVERY; MONTMORILLONITE; INTERCALATION; ADSORPTION; KAOLINITE; MINERALS; BEHAVIOR;
D O I
10.1071/CH13361
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Traditional applications of clay mineral mainly revolved around cosmetics and industrial products, but their scope of application is continuously expanding into pharmaceutics including drug delivery and tissue engineering. The interest in clays amongst the scientific community has increased dramatically in recent years due to its composition and structure which can be easily modified to serve different purposes. Largely due to structural flexibility and its small particle size, clay nanostructure can be modified to tune rheological and mechanical properties, and can entrap moisture to suit a particular application. Additionally, interest in the synthesis of polymer-clay nanocomposites in tissue engineering is growing as it is cheap, easily available, and environmentally-friendly. The structure of clay allows the interclaysion of different biomolecules between the clay layers. These biomolecules can be released in a controlled manner which can be utilised in drug delivery and cosmetic applications.
引用
收藏
页码:1315 / 1322
页数:8
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