New methodological approaches for assessing thrombus formation in cardiovascular disease

被引：3
作者：
Hosokawa, Kazuya [1 ]
Ohnishi-Wada, Tomoko [1 ]
Nagasato, Tomoka [1 ,2 ]
Sameshima-Kaneko, Hisayo [1 ]
Oyamada, Chiaki [1 ]
Dahlen, Jeffrey [3 ]
机构：
[1] Fujimori Kogyo Co Ltd, Res Inst, Yokohama, Kanagawa, Japan
[2] Grad Sch Med & Dent Sci, Dept Syst Biol Thromboregulat, Kagoshima, Japan
[3] Hikari Dx, San Diego, CA USA
来源：
KARDIOLOGIA POLSKA | 2020年 / 78卷 / 7-8期
关键词：
anticoagulant therapy; antiplatelet therapy; AR chip; PL chip; Total Thrombus-Formation Analysis System; PLATELET-FUNCTION ANALYZER; ACUTE CORONARY SYNDROMES; FLOW-CHAMBER SYSTEM; WARFARIN; THROMBOGENICITY; RIVAROXABAN; CLOPIDOGREL; ASPIRIN; DABIGATRAN; APIXABAN;
D O I：
10.33963/KP.15493
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Antiplatelet therapy is the mainstay preventive strategy for cardiovascular diseases, and dual antiplatelet therapy comprising aspirin and a P2Y12 inhibitor is the standard treatment for patients who underwent percutaneous coronary intervention. The Total Thrombus-Formation Analysis System (T-TAS) is a microchip flow-chamber system developed to evaluate overall thrombus formation under flow conditions, which is reportedly able to assess single and combined antithrombotic therapy. Here, we focus on this new system, T-TAS, and review its characteristics together with those of the conventional systems available for evaluation of antithrombotic therapies for cardiovascular diseases.
引用
收藏
页码：667 / 673
页数：7
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