An experimental and numerical investigation into the effects of diffuser valves in polymethylmethacrylate (PMMA) peristaltic micropumps

被引:17
作者
Hsu, Yi-Chu [1 ]
Li, Jia-Hao [1 ]
Le, Ngoc-Bich [1 ]
机构
[1] So Taiwan Univ Technol, Dept Mech Engn, Yung Kang, Tainan County, Taiwan
关键词
PMMA bonding; mu TAS; Peristaltic micropump; Diffuser valve; Four-phase control;
D O I
10.1016/j.sna.2008.07.002
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Utilizing micro-electromechanical systems (MEMS) techniques and a solvent-assisted bonding process, this study fabricates two peristaltic polymethylmethacrylate (PMMA) micropumps. In the first micropump, the actuation chambers are connected via straight microchannels with a uniform width and depth of 500 mu m and 200 mu m, respectively, while in the second micropump, the chambers are connected via tapered microchannels, which function as diffuser valves and yield a net one-way fluid flow. The experimental results indicate that the conventional and diffuser-type micropumps yield maximum flow rates of 262.4 mu l/min and 114.8 mu l/min, respectively. Furthermore, it is shown that the back pressure in the conventional micropump is 3.9 kPa, while that in the diffuser-type pump is 9.2 kPa. The flow rate spectra of the two micropumps are modeled numerically using an electronic-hydraulic analogy. The results obtained for the resonant excitation frequency of the two micropumps are consistent with those observed experimentally (400Hz). However, the flow rate predictions are slightly lower than the experimental values. Furthermore, the experimental flow rate spectrum has a broader bandwidth than the numerical equivalent. The discrepancy between the two sets of results is attributed to the overly simplistic modeling of the actuator-membrane mechanism in the equivalent circuit used to simulate the micropumps. (C) 2008 Elsevier B.V. All rights reserved.
引用
收藏
页码:149 / 157
页数:9
相关论文
共 15 条
  • [1] Development of peristaltic antithrombogenic micropumps for in vitro and ex vivo blood transportation tests
    Hsu, Yi-Chu
    Lin, Sung-Ju
    Hou, Ching-Cheng
    [J]. MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS, 2008, 14 (01): : 31 - 41
  • [2] Applying Taguchi methods for solvent-assisted PMMA bonding technique for static and dynamic μ-TAS devices
    Hsu, Yi-Chu
    Chen, Tang-Yuan
    [J]. BIOMEDICAL MICRODEVICES, 2007, 9 (04) : 513 - 522
  • [3] Pneumatic micropumps with serially connected actuation chambers
    Huang, Chun-Wei
    Huang, Song-Bin
    Lee, Gwo-Bin
    [J]. JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2006, 16 (11) : 2265 - 2272
  • [4] Kricka LJ, 1998, CLIN CHEM, V44, P2008
  • [5] LE NB, 2008, ASME MICR NAN HEAT T, P520
  • [6] Microfabricated plastic chips by hot embossing methods and their applications for DNA separation and detection
    Lee, GB
    Chen, SH
    Huang, GR
    Sung, WC
    Lin, YH
    [J]. SENSORS AND ACTUATORS B-CHEMICAL, 2001, 75 (1-2) : 142 - 148
  • [7] Microfabricated polycarbonate CE devices for DNA analysis
    Liu, YJ
    Ganser, D
    Schneider, A
    Liu, R
    Grodzinski, P
    Kroutchinina, N
    [J]. ANALYTICAL CHEMISTRY, 2001, 73 (17) : 4196 - 4201
  • [8] McDonald JC, 2000, ELECTROPHORESIS, V21, P27, DOI 10.1002/(SICI)1522-2683(20000101)21:1<27::AID-ELPS27>3.0.CO
  • [9] 2-C
  • [10] Fabrication of poly(methyl methacrylate) microfluidic chips by atmospheric molding
    Muck, A
    Wang, J
    Jacobs, M
    Chen, G
    Chatrathi, MP
    Jurka, V
    Vyborny, Z
    Spillman, SD
    Sridharan, G
    Schöning, MJ
    [J]. ANALYTICAL CHEMISTRY, 2004, 76 (08) : 2290 - 2297