Cyclodextrin nanoassemblies: a promising tool for drug delivery

被引：92

作者：

Bonnet, Veronique ^{[1
]}

Gervaise, Cedric ^{[1
,2
]}

Djedaini-Pilard, Florence ^{[1
]}

Furlan, Aurelien ^{[2
]}

Sarazin, Catherine ^{[2
]}

机构：

[1] Univ Picardie Jules Verne, CNRS, FRE 3517, LG2A,ICP FR3085, F-80039 Amiens, France

[2] Univ Picardie Jules Verne, CNRS, FRE3580, Genie Enzymat & Cellulaire, F-80039 Amiens, France

来源：

DRUG DISCOVERY TODAY | 2015年 / 20卷 / 09期

关键词：

AMPHIPHILIC-BETA-CYCLODEXTRINS; PHYSICOCHEMICAL PROPERTIES; STRUCTURAL-PROPERTIES; NANOPARTICLES; RECOGNITION; NANOSPHERES; VESICLES; IMPACT; CANCER; NANOTECHNOLOGY;

D O I：

10.1016/j.drudis.2015.05.008

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Among the biodegradable and nontoxic compounds that can form nanoparticles for drug delivery, amphiphilic cyclodextrins are very promising. Apart from ionic cyclodextrins, which have been extensively studied and reviewed because of their application in gene delivery, our purpose is to provide a clear description of the supramolecular assemblies of nonionic amphiphilic cyclodextrins, which can form nanoassemblies for controlled drug release. Moreover, we focus on the relationship between their structure and physicochemical characteristics, which is crucial for self assembly and drug delivery. We also highlight the importance of the nanopatticle technology preparation for the stability and application of this nanodevice.

引用

页码：1120 / 1126

页数：7

共 70 条

[1] Sulfated and non-sulfated amphiphilic-β-cyclodextrins:: Impact of their structural properties on the physicochemical properties of nanoparticles [J].

Abdelwahed, Wassim ;

Degobert, Ghania. ;

Dubes, Alix ;

Parrot-Lopez, Helene ;

Fessi, Hatem .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2008, 351 (1-2) :289-295

[2] Physico-chemical investigation of asymmetrical peptidolipidyl-cyclodextrins [J].

Angelova, Angelina ;

Fajolles, Christophe ;

Hocquelet, Celine ;

Djedaini-Pilard, Florence ;

Lesieur, Sylviane ;

Bonnet, Veronique ;

Perly, Bruno ;

Lebas, Genevieve ;

Mauclaire, Laurent .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2008, 322 (01) :304-314

[3] Squalene Based Nanocomposites: A New Platform for the Design of Multifunctional Pharmaceutical Theragnostics [J].

Arias, Jose L. ;

Reddy, L. Harivardhan ;

Othman, Mohammad ;

Gillet, Brigitte ;

Desmaele, Didier ;

Zouhiri, Fatima ;

Dosio, Franco ;

Gref, Ruxandra ;

Couvreur, Patrick .

ACS NANO, 2011, 5 (02) :1513-1521

[4] The acridone derivative MBLI-87 sensitizes breast cancer resistance protein-expressing xenografts to irinotecan [J].

Arnaud, O. ;

Boumendjel, A. ;

Geze, A. ;

Honorat, M. ;

Matera, E. L. ;

Guitton, J. ;

Stein, W. D. ;

Bates, S. E. ;

Falson, P. ;

Dumontet, C. ;

Di Pietro, A. ;

Payen, L. .

EUROPEAN JOURNAL OF CANCER, 2011, 47 (04) :640-648

[5]

Bilensoy E., 2011, CYCLODEXTRINS PHARM, DOI [10.1002/9780470926819, DOI 10.1002/9780470926819]

[6] Safety and efficacy of amphiphilic β-cyclodextrin nanoparticles for paclitaxel delivery [J].

Bilensoy, Erem ;

Gurkaynak, Oya ;

Dogan, A. Lale ;

Hincal, A. Atilla .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2008, 347 (1-2) :163-170

[7] Nanoparticles in cancer therapy and diagnosis [J].

Brigger, I ;

Dubernet, C ;

Couvreur, P .

ADVANCED DRUG DELIVERY REVIEWS, 2002, 54 (05) :631-651

[8] Nanoparticles derived from amphiphilic γ-cyclodextrins [J].

Cavalli, Roberta ;

Trotta, Francesco ;

Carlotti, M. Eugenia ;

Possetti, Barbara ;

Trotta, Michele .

JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, 2007, 57 (1-4) :657-661

[9] Miscellaneous nanoaggregates made of β-CD esters synthesised by an enzymatic pathway [J].

Choisnard, L. ;

Geze, A. ;

Yameogo, B. G. J. ;

Putaux, J.-L. ;

Wouessidjewe, D. .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2007, 344 (1-2) :26-32

[10]

Choisnard L, 2005, J PHARM PHARM SCI, V8, P593

← 1 2 3 4 5 6 7 →