Gene expression signatures of pediatric myelodysplastic syndromes are associated with risk of evolution into acute myeloid leukemia

被引:6
作者
Bresolin, S. [1 ]
Trentin, L. [1 ,2 ]
Zecca, M. [3 ]
Giordan, M. [1 ]
Sainati, L. [1 ]
Locatelli, F. [4 ,5 ]
Basso, G. [1 ]
te Kronnie, G. [1 ]
机构
[1] Univ Padua, Dept Pediat, SSD Ematol Clin Sperimentale, Padua, Italy
[2] Univ Ulm, Dept Pediat & Adolescent Med, Ulm, Germany
[3] Fdn IRCCS Policlin San Matteo, Pavia, Italy
[4] IRCSS Osped Pediat Bambino Gesu, Dept Pediat Hematol Oncol, Rome, Italy
[5] Univ Pavia, I-27100 Pavia, Italy
关键词
JUVENILE MYELOMONOCYTIC LEUKEMIA; CLASSIFICATION; CELLS;
D O I
10.1038/leu.2012.35
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1717 / 1719
页数:4
相关论文
共 15 条
[1]   Gene Expression-Based Classification As an Independent Predictor of Clinical Outcome in Juvenile Myelomonocytic Leukemia [J].
Bresolin, Silvia ;
Zecca, Marco ;
Flotho, Christian ;
Trentin, Luca ;
Zangrando, Andrea ;
Sainati, Laura ;
Stary, Jan ;
de Moerloose, Barbara ;
Hasle, Henrik ;
Niemeyer, Charlotte M. ;
Kronnie, Geertruy Te ;
Locatelli, Franco ;
Basso, Giuseppe .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (11) :1919-1927
[2]   Gene expression profiling of Polycomb, Hox and Meis genes in patients with acute myeloid leukaemia [J].
Grubach, Lykke ;
Juhl-Christensen, Caroline ;
Rethmeier, Anita ;
Olesen, Lene Hyldahl ;
Aggerholm, Anni ;
Hokland, Peter ;
Ostergaard, Mette .
EUROPEAN JOURNAL OF HAEMATOLOGY, 2008, 81 (02) :112-122
[3]   Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia Study Group [J].
Haferlach, Torsten ;
Kohlmann, Alexander ;
Wieczorek, Lothar ;
Basso, Giuseppe ;
Kronnie, Geertruy Te ;
Bene, Marie-Christine ;
De Vos, John ;
Hernandez, Jesus M. ;
Hofmann, Wolf-Karsten ;
Mills, Ken I. ;
Gilkes, Amanda ;
Chiaretti, Sabina ;
Shurtleff, Sheila A. ;
Kipps, Thomas J. ;
Rassenti, Laura Z. ;
Yeoh, Allen E. ;
Papenhausen, Peter R. ;
Liu, Wei-min ;
Williams, P. Mickey ;
Foa, Robin .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (15) :2529-2537
[4]   A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases [J].
Hasle, H ;
Niemeyer, CM ;
Chessells, JM ;
Baumann, I ;
Bennett, JM ;
Kerndrup, G ;
Head, DR .
LEUKEMIA, 2003, 17 (02) :277-282
[5]   Advances in the prognostication and management of advanced MDS in children [J].
Hasle, Henrik ;
Niemeyer, Charlotte M. .
BRITISH JOURNAL OF HAEMATOLOGY, 2011, 154 (02) :185-195
[6]   Refractory anemia in childhood:: a retrospective analysis of 67 patients with particular reference to monosomy 7 [J].
Kardos, G ;
Baumann, I ;
Passmore, SJ ;
Locatelli, F ;
Hasle, H ;
Schultz, KR ;
Stary, J ;
Schmitt-Graeff, A ;
Fischer, A ;
Harbott, J ;
Chessells, JI ;
Hann, I ;
Fenu, S ;
Rajnoldi, AC ;
Kerndrup, G ;
van Wering, E ;
Rogge, T ;
Nöllke, P ;
Niemeyer, CM .
BLOOD, 2003, 102 (06) :1997-2003
[7]   Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2′-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis [J].
Liu, Wenli ;
Lee, Hyun Woo ;
Liu, Yueqin ;
Wang, Ruihong ;
Rodgers, Griffin P. .
BLOOD, 2010, 116 (23) :4938-4947
[8]   Microarray-based classifiers and prognosis models identify subgroups with distinct clinical outcomes and high risk of AML transformation of myelodysplastic syndrome [J].
Mills, Ken I. ;
Kohlmann, Alexander ;
Williams, P. Mickey ;
Wieczorek, Lothar ;
Liu, Wei-min ;
Li, Rachel ;
Wei, Wen ;
Bowen, David T. ;
Loeffler, Helmut ;
Hernandez, Jesus M. ;
Hofmann, Wolf-Karsten ;
Haferlach, Torsten .
BLOOD, 2009, 114 (05) :1063-1072
[9]   Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia: molecular classification and treatment options [J].
Niemeyer, Charlotte Marie ;
Kratz, Christian Peter .
BRITISH JOURNAL OF HAEMATOLOGY, 2008, 140 (06) :610-624
[10]   Accurate ranking of differentially expressed genes by a distribution-free shrinkage approach [J].
Opgen-Rhein, Rainer ;
Strimmer, Korbinian .
STATISTICAL APPLICATIONS IN GENETICS AND MOLECULAR BIOLOGY, 2007, 6