Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells

被引：199
|
作者：
Chanvitayapongs, S
DraczynskaLusiak, B
Sun, AY
机构：
[1] UNIV MISSOURI,DEPT PHARMACOL,COLUMBIA,MO 65212
[2] UNIV MISSOURI,SCH MED,COLUMBIA,MO 65212
来源：
NEUROREPORT | 1997年 / 8卷 / 06期
关键词：
antioxidants; cell death; Na+; K+-ATPase; oxidative stress; resveratrol; vitamins E and C;
D O I：
10.1097/00001756-199704140-00035
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The goal of this study was to investigate the effect of resveratrol, an active ingredient found in grapes and other plant products, in ameliorating oxidative stress. Oxidative stress was induced by addition of Fe2+ and t-butyl hydroperoxide to the cultured PC12 cell medium. Resveratrol, vitamins C and/or E, were added to the cell culture medium during oxidative stress. The combination of resveratrol and vitamins C and/or E was more effective in protecting the cell than was any of these three antioxidants alone.
引用
收藏
页码：1499 / 1502
页数：4
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