Lymphadenectomy Alone Is a Feasible Option in Managing Incidentally-detected Early-stage Cervical Cancer After Simple Hysterectomy without Intermediate-risk Factors: An Application of the Concept of Less Radical Surgery

被引：1

作者：

Jeon, Hye Won ^{[1
]}

Suh, Dong Hoon ^{[2
]}

Kim, Kidong ^{[2
]}

No, Jae Hong ^{[2
]}

Kim, Yong-Beom ^{[2
]}

机构：

[1] SMG SNU Boramae Med Ctr, Dept Obstet & Gynecol, Seoul, South Korea

[2] Seoul Natl Univ, Bundang Hosp, Dept Obstet & Gynecol, Songnam, South Korea

来源：

ANTICANCER RESEARCH | 2013年 / 33卷 / 11期

关键词：

Cervical cancer; simple hysterectomy; intermediate risk factor; less radical surgery; GYNECOLOGIC-ONCOLOGY-GROUP; PELVIC RADIATION-THERAPY; PARAMETRIAL INVOLVEMENT; PROGNOSTIC-FACTORS; VASCULAR INVASION; RANDOMIZED-TRIAL; ADJUVANT THERAPY; I CARCINOMA; IDENTIFICATION; CHEMOTHERAPY;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Aim: To assess the feasibility of less radical surgery in patients with incidentally-detected cervical cancer at simple hysterectomy. Patients and Methods: High-risk factors (HFs) were evaluated in 104 patients who underwent radical hysterectomy and lymphadenectomy for the treatment of stage IA1-IB1 cervical cancer according to intermediate-risk factors (IFs). Results: Thirty-three patients without IFs had no HFs. As the number of IFs increased, the number of HFs increased (p=0.009). Multivariate analysis revealed that lymph node metastasis was the only independent risk factor for parametrial involvement (hazard ratio, 31.3; 95% confidence interval, 1.6-599.4; p=0.022). An absence of IFs was associated with a longer progression-free survival than the presence of IFs in the subgroup analysis of favorable histologies (p=0.044). Conclusion: HFs could be excluded in stage IA1-IB1 cervical cancer without IFs. Omitting parametrectomy seems a feasible option for selected patients with incidentally-detected early-stage cervical cancer at simple hysterectomy, without IFs.

引用

页码：5135 / 5141

页数：7