Catalytic asymmetric exo-selective [6+3] cycloaddition of iminoesters with fulvenes

被引：48

作者：

Potowski, Marco ^{[1
,2
]}

Antonchick, Andrey P. ^{[1
]}

Waldmann, Herbert ^{[1
,2
]}

机构：

[1] Max Planck Inst Mol Physiol, D-44227 Dortmund, Germany

[2] TU Dortmund, Fac Chem, D-44227 Dortmund, Germany

来源：

CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 71期

基金：

欧洲研究理事会;

关键词：

ENANTIOSELECTIVE 3+2 CYCLOADDITION; AZOMETHINE YLIDES; 1,3-DIPOLAR CYCLOADDITION; TRIFLUOROMETHYLATED PYRROLIDINES; CONSTRUCTION; PIPERIDINES; OLEFINS; ORGANOCATALYSTS; ESTERS;

D O I：

10.1039/c3cc43824d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel exo-selective [6+3] cycloaddition approach for the highly enantioselective synthesis of polysubstituted piperidines was developed. The developed methodology was applied in a one-pot [6+3]-[4+2] dicycloaddition, allowing the construction of structurally and stereochemically rich polycyclic compounds from simple building blocks.

引用

页码：7800 / 7802

页数：3

共 37 条

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