Avidity of IgG to Rickettsia prowazekii and the presence of specific IgM in blood sera for retrospective analysis of the 1998 epidemic typhus outbreak in Russia
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作者:
Chekanova, Tatiana
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Cent Res Inst Epidemiol, Lab Epidemiol Nat Focal Infect, 3A Novogireyevskaya St, Moscow 111123, RussiaCent Res Inst Epidemiol, Lab Epidemiol Nat Focal Infect, 3A Novogireyevskaya St, Moscow 111123, Russia
Chekanova, Tatiana
[1
]
Shpynov, Stanislav
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Omsk Res Inst Nat Focal Infect, Omsk 644080, RussiaCent Res Inst Epidemiol, Lab Epidemiol Nat Focal Infect, 3A Novogireyevskaya St, Moscow 111123, Russia
Shpynov, Stanislav
[2
]
机构:
[1] Cent Res Inst Epidemiol, Lab Epidemiol Nat Focal Infect, 3A Novogireyevskaya St, Moscow 111123, Russia
[2] Omsk Res Inst Nat Focal Infect, Omsk 644080, Russia
The authors applied a new methodological approach based not only on the study of IgM/IgG to Rickettsia prowazekii in sera, but also on the estimation of the avidity index of specific IgG. The data allowed the authors to draw new conclusions about the 1998 epidemic typhus outbreak in Russia.