Von Willebrand's disease and angiodysplasia treated with thalidomide

被引：27

作者：

Hirri, HM ^{[1
]}

Green, PJ

Lindsay, J

机构：

[1] Portsmouth Hosp NHS Trust, London, England

[2] London NHS Trust, London, England

来源：

HAEMOPHILIA | 2006年 / 12卷 / 03期

关键词：

Angiodysplasia; Gastrointestinal Bleeding; Thalidomide; Von Willebrand's disease;

D O I：

10.1111/j.1365-2516.2006.01210.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 54-year-old man with type IIB VWD and severe angiodysplasia had such a large blood loss from the bowel that it was difficult to keep up with transfusion requirements. Treatment with factor eight concentrate barely slowed the loss. D.D.A.V.P., Octreotide, and recombinant activated Factor VII, tried separately, were ineffective. The use of Thalidomide at a dose of 150 mg daily has rendered him free from blood loss for the last six months and we suggest would be worth a trial in similar cases.

引用

页码：285 / 286

页数：2

共 5 条

[1] Thalidomide for treatment of severe intestinal bleeding [J].