Cross-correlation based methods for estimating the functional connectivity in populations of cortical neurons
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作者:
Ide, A. N.
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Univ Genoa, DIBE, NBT Grp, Via Opera Pia 11A, Genoa, Italy
Univ Genoa, Neurolab, Genoa, ItalyUniv Genoa, DIBE, NBT Grp, Via Opera Pia 11A, Genoa, Italy
Ide, A. N.
[1
,4
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Chiappalone, M.
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Univ Genoa, DIBE, NBT Grp, Via Opera Pia 11A, Genoa, Italy
Italian Inst Technol IIT, Unit Neurosci & Brain Technol, Genoa, ItalyUniv Genoa, DIBE, NBT Grp, Via Opera Pia 11A, Genoa, Italy
Chiappalone, M.
[1
,2
]
Berdondini, L.
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Univ Neuchatel, IMT, Actuators & Microsyst Lab, Neuchatel, SwitzerlandUniv Genoa, DIBE, NBT Grp, Via Opera Pia 11A, Genoa, Italy
Berdondini, L.
[3
]
Sanguineti, V.
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Univ Genoa, Neurolab, Genoa, ItalyUniv Genoa, DIBE, NBT Grp, Via Opera Pia 11A, Genoa, Italy
Sanguineti, V.
[4
]
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Martinoia, S.
[1
]
机构:
[1] Univ Genoa, DIBE, NBT Grp, Via Opera Pia 11A, Genoa, Italy
[2] Italian Inst Technol IIT, Unit Neurosci & Brain Technol, Genoa, Italy
In this paper we estimate the functional connectivity in in-vitro cultured cortical neurons plated into high-density passive microelectrodes arrays. We compare standard and partial correlation methods in order to find out the main pathways between two electrodes. In summary, while standard correlation considers Just pairs of electrodes, giving a general overview of the network, partial correlation can give more details about the connectivity map due to the cancellation of indirect connections.
机构:
Duke Univ, Dept Biomed Engn, Durham, NC 27710 USADuke Univ, Dept Biomed Engn, Durham, NC 27710 USA
Zhuang, Katie Z.
Lebedev, Mikhail A.
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机构:
Duke Univ, Dept Biomed Engn, Durham, NC 27710 USA
Duke Univ, Dept Neurobiol, Durham, NC 27710 USADuke Univ, Dept Biomed Engn, Durham, NC 27710 USA
Lebedev, Mikhail A.
Nicolelis, Miguel A. L.
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机构:
Duke Univ, Dept Biomed Engn, Durham, NC 27710 USA
Duke Univ, Dept Neurobiol, Durham, NC 27710 USA
Duke Univ, Dept Psychol & Neurosci, Durham, NC 27710 USA
Duke Univ, Ctr Neuroengn, Durham, NC 27710 USA
ELS IINN, Natal, RN, BrazilDuke Univ, Dept Biomed Engn, Durham, NC 27710 USA