Clinical research in critical care. Difficulties and perspectives

被引：8

作者：

Latour-Perez, J. ^{[1
,2
]}

机构：

[1] Hosp Gen Univ Elche, Serv Med Intens, Elche, Spain

[2] Univ Miguel Herndndez, Dept Med Clin, Sant Joan dAlacant, Spain

来源：

MEDICINA INTENSIVA | 2018年 / 42卷 / 03期

关键词：

Critical care; Clinical trials; Diffusion of innovation; Evidence-based medicine; Precision medicine; RESPIRATORY-DISTRESS-SYNDROME; RANDOMIZED CONTROLLED-TRIALS; SELECTIVE DIGESTIVE DECONTAMINATION; ILL PATIENTS; INTENSIVE-CARE; PERSONALIZED MEDICINE; REDUCING WASTE; SEPTIC SHOCK; BIOMEDICAL-RESEARCH; INCREASING VALUE;

D O I：

10.1016/j.medin.2017.07.008

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

In the field of Intensive Care Medicine, improved survival has resulted from better patient care, the early detection of clinical deterioration, and the prevention of iatrogenic complications, while research on new treatments has been followed by an overwhelming number of disappointments. The origins of these fiascos must be sought in the conjunction of methodological problems - common to other disciplines - and the particularities of critically ill patients. The present article discusses both aspects and suggests some options for progress. (C) 2017 Elsevier Espana, S.L.U. y SEMICYUC. All rights reserved.

引用

页码：184 / 195

页数：12

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