A method for analyzing temporal patterns of variability of a time series from Poincare plots

Fishman M, Jacono FJ, Park S, Jamasebi R, Thungtong A, Loparo KA, Dick TE. A method for analyzing temporal patterns of variability of a time series from Poincare plots. J Appl Physiol 113: 297-306, 2012. First published May 3, 2012; doi: 10.1152/japplphysiol.01377.2010.-The Poincare plot is a popular two-dimensional, time series analysis tool because of its intuitive display of dynamic system behavior. Poincare plots have been used to visualize heart rate and respiratory pattern variabilities. However, conventional quantitative analysis relies primarily on statistical measurements of the cumulative distribution of points, making it difficult to interpret irregular or complex plots. Moreover, the plots are constructed to reflect highly correlated regions of the time series, reducing the amount of nonlinear information that is presented and thereby hiding potentially relevant features. We propose temporal Poincare variability (TPV), a novel analysis methodology that uses standard techniques to quantify the temporal distribution of points and to detect nonlinear sources responsible for physiological variability. In addition, the analysis is applied across multiple time delays, yielding a richer insight into system dynamics than the traditional circle return plot. The method is applied to data sets of R-R intervals and to synthetic point process data extracted from the Lorenz time series. The results demonstrate that TPV complements the traditional analysis and can be applied more generally, including Poincare plots with multiple clusters, and more consistently than the conventional measures and can address questions regarding potential structure underlying the variability of a data set.