Synthesis of perfluoroalkylated β-alanine and some peptide derivatives:: an access to original surfactants

被引：9

作者：

Özer, MS ^{[1
]}

Gérardin-Charbonnier, C ^{[1
]}

Thiébaut, S ^{[1
]}

Rodehüser, L ^{[1
]}

Selve, C ^{[1
]}

机构：

[1] Univ Henri Poincare, Fac Sci, CNRS UHP,UMR 7565,INCM FU 008, Lab Chim Phys Organ & Colloidale, F-54506 Vandoeuvre Nancy, France

来源：

AMINO ACIDS | 1999年 / 16卷 / 3-4期

关键词：

amino acids; perfluorinated compounds; surfactants; complexing properties; carnosine; beta-amino acids; blood substitutes;

D O I：

10.1007/BF01388177

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The reaction of amines or sodium azide with 3-perfluoroalkyl-3-fluoroprop-2-enoate, followed by hydrogenation, affords perfluoroalkylated beta-alanine analogues in very good yields. These compounds can be linked via an amide bond to produce peptide analogues such as carnosine or carcinine derivatives, which could have surfactive and complexing properties.

引用

页码：381 / 389

页数：9

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