Promises and challenges of metabolomics in SLE

被引:13
作者
Ding, Huihua [1 ]
Mohan, Chandra [1 ]
机构
[1] Univ Houston, Dept Biomed Engn, 3605 Cullen Blvd, Houston, TX 77204 USA
关键词
D O I
10.1038/nrrheum.2016.163
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Despite a multitude of confounding variables, common themes are emerging in metabolomic studies of systemic lupus erythematosus (SLE). Newly revealed metabolites and pathways are likely to complement the biomarkers and insights into SLE pathogenesis that are emerging from genomic, transcriptomic and proteomic studies.
引用
收藏
页码:627 / U17
页数:2
相关论文
共 10 条
  • [1] Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjogren's Syndrome and Systemic Sclerosis
    Bengtsson, Anders A.
    Trygg, Johan
    Wuttge, Dirk M.
    Sturfelt, Gunnar
    Theander, Elke
    Donten, Magdalena
    Moritz, Thomas
    Sennbro, Carl-Johan
    Torell, Frida
    Lood, Christian
    Surowiec, Izabella
    Rannar, Stefan
    Lundstedt, Torbjorn
    [J]. PLOS ONE, 2016, 11 (07):
  • [2] Human metabolic phenotype diversity and its association with diet and blood pressure
    Holmes, Elaine
    Loo, Ruey Leng
    Stamler, Jeremiah
    Bictash, Magda
    Yap, Ivan K. S.
    Chan, Queenie
    Ebbels, Tim
    De Iorio, Maria
    Brown, Ian J.
    Veselkov, Kirill A.
    Daviglus, Martha L.
    Kesteloot, Hugo
    Ueshima, Hirotsugu
    Zhao, Liancheng
    Nicholson, Jeremy K.
    Elliott, Paul
    [J]. NATURE, 2008, 453 (7193) : 396 - U50
  • [3] The relationship between BMI and metabolomic profiles: a focus on amino acids
    Morris, Ciara
    O'Grada, Colm
    Ryan, Miriam
    Roche, Helen M.
    Gibney, Michael J.
    Gibney, Eileen R.
    Brennan, Lorraine
    [J]. PROCEEDINGS OF THE NUTRITION SOCIETY, 2012, 71 (04) : 634 - 638
  • [4] 1H NMR-based metabolomic study of metabolic profiling for systemic lupus erythematosus
    Ouyang, X.
    Dai, Y.
    Wen, J. L.
    Wang, L. X.
    [J]. LUPUS, 2011, 20 (13) : 1411 - 1420
  • [5] Tolerance to apoptotic cells is regulated by indoleamine 2,3-dioxygenase
    Ravishankar, Buvana
    Liu, Haiyun
    Shinde, Rahul
    Chandler, Phillip
    Baban, Babak
    Tanaka, Masato
    Munn, David H.
    Mellor, Andrew L.
    Karlsson, Mikael C. I.
    McGaha, Tracy L.
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (10) : 3909 - 3914
  • [6] Identification of urinary metabolites that distinguish membranous lupus nephritis from proliferative lupus nephritis and focal segmental glomerulosclerosis
    Romick-Rosendale, Lindsey E.
    Brunner, Hermine I.
    Bennett, Michael R.
    Mina, Rina
    Nelson, Shannen
    Petri, Michelle
    Kiani, Adnan
    Devarajan, Prasad
    Kennedy, Michael A.
    [J]. ARTHRITIS RESEARCH & THERAPY, 2011, 13 (06)
  • [7] Saegusa J, 2014, CLIN EXP RHEUMATOL, V32, P148
  • [8] Metabolic Disturbances Associated with Systemic Lupus Erythematosus
    Wu, Tianfu
    Xie, Chun
    Han, Jie
    Ye, Yujin
    Weiel, Jim
    Li, Quan
    Blanco, Irene
    Ahn, Chul
    Olsen, Nancy
    Putterman, Chaim
    Saxena, Ramesh
    Mohan, Chandra
    [J]. PLOS ONE, 2012, 7 (06):
  • [9] Serum metabolomic profiling in patients with systemic lupus erythematosus by GC/MS
    Yan, Bei
    Huang, Jia
    Zhang, Chunmei
    Hu, Xin
    Gao, Ming
    Shi, Aixin
    Zha, Weibin
    Shi, Luyi
    Huang, Cibo
    Yang, Liping
    [J]. MODERN RHEUMATOLOGY, 2016, 26 (06) : 914 - 922
  • [10] Esophageal Cancer Metabolite Biomarkers Detected by LC-MS and NMR Methods
    Zhang, Jian
    Bowers, Jeremiah
    Liu, Lingyan
    Wei, Siwei
    Gowda, G. A. Nagana
    Hammoud, Zane
    Raftery, Daniel
    [J]. PLOS ONE, 2012, 7 (01):