Analysis of apolipoprotein E gene polymorphism in populations of the Volga-Ural region

被引：1

作者：

Mustafina, OE ^{[1
]}

Tuktarova, IA ^{[1
]}

Bikmeeva, AM ^{[1
]}

Nasibullin, TR ^{[1
]}

Khusnutdinova, EK ^{[1
]}

机构：

[1] Russian Acad Sci, Ufa Sci Ctr, Inst Biochem & Genet, Ufa 450054, Bashkortostan, Russia

来源：

RUSSIAN JOURNAL OF GENETICS | 2001年 / 37卷 / 04期

基金：

俄罗斯基础研究基金会;

关键词：

D O I：

10.1023/A:1016670913825

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Polymorphism at the apolipoprotein E gene (apoE) in populations of the Volga-Ural region was studied by means of polymerase chain reaction. In the region examined the population-specific patterns of the apoE alleles and genotypes frequency distribution were established. The results obtained were compared with the literature data on the apoE polymorphism in other world populations. Substantial heterogeneity of different ethnic populations in respect to the apoE genotypes distribution and frequency was revealed.

引用

页码：448 / 452

页数：5

共 20 条

[1] Education, activity, health, blood pressure and apolipoprotein E as predictors of cognitive change in old age: A review [J].

Anstey, K ;

Christensen, H .

GERONTOLOGY, 2000, 46 (03) :163-177

[2] APOLIPOPROTEIN GENETIC-VARIATION AND HUMAN-DISEASE [J].

BRESLOW, JL .

PHYSIOLOGICAL REVIEWS, 1988, 68 (01) :85-132

[3] GENETIC-REGULATION OF APOLIPOPROTEINS [J].

BRESLOW, JL .

AMERICAN HEART JOURNAL, 1987, 113 (02) :422-427

[4]

Corbo RM, 1999, HUM BIOL, V71, P933

[5] GENETIC-HETEROGENEITY OF APOLIPOPROTEIN-E AND ITS INFLUENCE ON PLASMA-LIPID AND LIPOPROTEIN LEVELS [J].

DEKNIJFF, P ;

VANDENMAAGDENBERG, AMJM ;

FRANTS, RR ;

HAVEKES, LM .

HUMAN MUTATION, 1994, 4 (03) :178-194

[6]

EHNHOLM C, 1986, J LIPID RES, V27, P227

[7]

ETO M, 1989, CLIN GENET, V36, P183

[8]

EVANS AE, 1993, HUM GENET, V92, P191

[9]

HIXSON JE, 1990, J LIPID RES, V31, P545

[10] Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study [J].

Hofman, A ;

Ott, A ;

Breteler, MMB ;

Bots, ML ;

Slooter, AJC ;

vanHarskamp, F ;

vanDuijn, CN ;

Van Broeckhoven, C ;

Grobbee, DE .

LANCET, 1997, 349 (9046) :151-154

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