Three-membered ring sesquiterpenoids with NGF-potentiating activity from the roots of Valeriano fauriei

被引：20
作者：
Guo, YQ
Xu, J
Li, YS
Yamakuni, T
Ohizumi, Y [1 ]
机构：
[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Dept Pharmaceut Mol Biol, Sendai, Miyagi 9808578, Japan
[2] Shenyang Pharmaceut Univ, Res Dept Nat Med, Shenyang, Peoples R China
来源：
PLANTA MEDICA | 2006年 / 72卷 / 04期
关键词：
D O I：
10.1055/s-2005-916210
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three novel three-membered ring sesquiterpenoids, named kissoone A (1), kissoone B (2), and its acetylated product, kissoone C (3), were isolated from the roots of Valeriana fauriei. Their structures were elucidated on the basis of spectroscopic analysis. Compounds 2 and 3 showed enhancing activity on nerve growth factor (NGF)-mediated neurite outgrowth in PC 12D cells.
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收藏
页码：373 / 375
页数：3
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