Energy Migration Engineering of Bright Rare-Earth Upconversion Nanoparticles for Excitation by Light-Emitting Diodes

被引:89
作者
Zhong, Yeteng [1 ,2 ]
Rostami, Iman [1 ]
Wang, Zihua [1 ]
Dai, Hongjie [2 ]
Hu, Zhiyuan [1 ,3 ,4 ,5 ]
机构
[1] Chinese Acad Sci, Natl Ctr Nanosci & Technol China, Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
[2] Stanford Univ, Dept Chem, Stanford, CA 94305 USA
[3] Beijing Proteome Res Ctr, Beijing Inst Radiat Med, Beijing 102206, Peoples R China
[4] Inst Syst Biol, Seattle, WA 98109 USA
[5] Yangtze River Delta Acad Nanotechnol & Ind Dev Re, Jiaxing 314000, Zhejiang, Peoples R China
基金
中国国家自然科学基金; 国家高技术研究发展计划(863计划);
关键词
SILICA NANOPARTICLES; DRUG-DELIVERY; NANOPHOSPHORS; LUMINESCENCE; THERAPY; NANOPROBES;
D O I
10.1002/adma.201502272
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel Nd3+-sensitized upconversion nanoparticle (UCNP) that can be excited by near-infrared 740 nm light-emitting diode (LED) lamps with bright upconversion luminescence is designed. Yb3+ ion distribution is engineered to increase the energy migration efficiency. The benefit of the novel LED-excited UCNPs is demonstrated by imaging of breast cancer cells and enabling an economic handheld semiquantitative visual measurement device.
引用
收藏
页码:6418 / +
页数:6
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