Stem Cell Therapy for Tendon Injury

被引:25
作者
Chen, Hsin-Shui [1 ,2 ]
Chen, Yi-Lin [3 ,4 ]
Harn, Horng-Tyh [2 ,5 ,6 ]
Lin, Jung-Sheng [7 ]
Lin, Shinn-Zong [8 ,9 ,10 ]
机构
[1] China Med Univ, Beigang Hosp, Dept Phys Med & Rehabil, Yunlin, Taiwan
[2] China Med Univ, Sch Med, Taichung, Taiwan
[3] Natl Ilan Univ, Grad Inst Biotechnol, Ilan, Taiwan
[4] Natl Ilan Univ, Dept Life Sci, Ilan, Taiwan
[5] China Med Univ Hosp, Dept Pathol, Taichung, Taiwan
[6] Gwo Xi Stem Cell Appl Technol, Dept Stem Cell Appl Technol, Hsinchu, Taiwan
[7] Beigang Hosp, Dept Urol Surg, Yunlin, Taiwan
[8] China Med Univ Hosp, Ctr Neuropsychiat, Taichung, Taiwan
[9] China Med Univ, Beigang Hosp, Dept Neurosurg, Yunlin, Taiwan
[10] China Med Univ, Grad Inst Immunol, Taichung, Taiwan
关键词
Tendon injury; Cell therapy; Stem cell; TOPICAL GLYCERYL TRINITRATE; SHOCK-WAVE THERAPY; NONINSERTIONAL ACHILLES TENDINOPATHY; RANDOMIZED CONTROLLED-TRIAL; SCLEROSING POLIDOCANOL INJECTIONS; LIGHT-MICROSCOPIC HISTOLOGY; ROTATOR CUFF TEARS; DOUBLE-BLIND; FLEXOR TENDINITIS; PHYSICAL-ACTIVITY;
D O I
10.3727/096368912X655118
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Tendon injury may occur suddenly or progressively, and can be divided into tendon rupture or tendinopathy based on the severity of injury. It is frequently found in professional or nonprofessional people who are making repetitive movements. In aged people, tendon degeneration becomes obvious; their tendon injuries are then frequently evident. No effective therapies for tendon injury are currently available. In this article, we review the tendon structure, mechanisms of tendon injury, and tendon healing process. More importantly, cell-based therapies for tendon injury are fully addressed, which will play an important role for tendon therapy in the near future.
引用
收藏
页码:677 / 684
页数:8
相关论文
共 100 条
  • [1] Achilles tendon problems: Not just an orthopaedic issue
    Ames, Paul Richard Julian
    Longo, Umile Giuseppe
    Denaro, Vincenzo
    Maffulli, Nicola
    [J]. DISABILITY AND REHABILITATION, 2008, 30 (20-22) : 1646 - 1650
  • [2] ASTROM M, 1992, ACTA ORTHOP SCAND, V63, P631
  • [3] AUCLAIR J, 1989, CURR THER RES CLIN E, V46, P782
  • [4] Autologous mesenchymal stem cell-mediated repair of tendon
    Awad, HA
    Butler, DL
    Boivin, GP
    Smith, FNL
    Malaviya, P
    Huibregtse, B
    Caplan, AI
    [J]. TISSUE ENGINEERING, 1999, 5 (03): : 267 - 277
  • [5] Benjamin M, 1995, REPETITIVE MOTION DISORDERS OF THE UPPER EXTREMITY, P185
  • [6] Reactive oxygen species and tendinopathy: do they matter?
    Bestwick, CS
    Maffulli, N
    [J]. BRITISH JOURNAL OF SPORTS MEDICINE, 2004, 38 (06) : 672 - 674
  • [7] Oxidative energy metabolism in equine tendon cells
    Birch, HL
    Rutter, GA
    Goodship, AE
    [J]. RESEARCH IN VETERINARY SCIENCE, 1997, 62 (02) : 93 - 97
  • [8] Rotator cuff repair with periosteum for enhancing tendon-bone healing: a biomechanical and histological study in rabbits
    Chang, Chih-Hsiang
    Chen, Chih-Hwa
    Su, Chun-Yi
    Liu, Hsien-Tao
    Yu, Chung-Ming
    [J]. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 2009, 17 (12) : 1447 - 1453
  • [9] Enhancement of rotator cuff tendon-bone healing with injectable periosteum progenitor cells-BMP-2 hydrogel in vivo
    Chen, Chih-Hwa
    Chang, Chih-Hsiang
    Wang, Kun-Chung
    Su, Chun-I
    Liu, Hsien-Tao
    Yu, Chung-Ming
    Wong, Chak-Bor
    Wang, I-Chun
    Whu, Shu Wen
    Liu, Hsia-Wei
    [J]. KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 2011, 19 (09) : 1597 - 1607
  • [10] Efficacy of hESC-MSCs in knitted silk-collagen scaffold for tendon tissue engineering and their roles
    Chen, Jia Lin
    Yin, Zi
    Shen, Wei Liang
    Chen, Xiao
    Heng, Boon Chin
    Zou, Xiao Hui
    Ouyang, Hong Wei
    [J]. BIOMATERIALS, 2010, 31 (36) : 9438 - 9451