Abnormalities in Host Defense Associated with HIV Infection

被引：9
作者：
Beck, James M. [1 ,2 ]
机构：
[1] Vet Affairs Eastern Colorado Hlth Care Syst, Med Serv, Denver, CO 80220 USA
[2] Univ Colorado, Sch Med, Dept Med, Aurora, CO 80045 USA
来源：
CLINICS IN CHEST MEDICINE | 2013年 / 34卷 / 02期
关键词：
HIV infections; Lung diseases; Macrophages; alveolar; T-lymphocytes; B-lymphocytes; Bronchoalveolar lavage; HUMAN-IMMUNODEFICIENCY-VIRUS; TUMOR-NECROSIS-FACTOR; PNEUMOCYSTIS-CARINII-PNEUMONIA; BRONCHOALVEOLAR LAVAGE CELLS; IMMUNE-DEFICIENCY-SYNDROME; PERIPHERAL-BLOOD MONOCYTES; CD8(+) T-LYMPHOCYTES; TNF-ALPHA RELEASE; ALVEOLAR MACROPHAGES; OPPORTUNISTIC INFECTIONS;
D O I：
10.1016/j.ccm.2013.01.003
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
The broad variety of pulmonary infections encountered in human immunodeficiency virus (HIV)-infected individuals demonstrates that the host defense network is impaired. An improved understanding of these events in the lung can lead to specific interventions aimed at restoration of deficient function. This review summarizes the pulmonary host defense deficits in HIV-infected individuals, focusing on lymphocytes, alveolar macrophages, and neutrophils.
引用
收藏
页码：143 / +
页数：12
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