Serum fetuin-A levels are associated with the presence and severity of coronary artery disease in patients with type 2 diabetes

被引：42
作者：
Zhao, Zi-Wen [1 ]
Lin, Chao-Gui [1 ]
Wu, Ling-Zhen [1 ]
Luo, Yu-Kun [1 ]
Fan, Lin [1 ]
Dong, Xian-feng [1 ]
Zheng, Hong [1 ]
机构：
[1] Fujian Med Univ, Fujian Inst Coronary Artery Dis, Union Hosp, Dept Cardiol, Fuzhou 350001, Peoples R China
来源：
BIOMARKERS | 2013年 / 18卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Biomarker; coronary artery disease; diabetes; fetuin-A; MYOCARDIAL-INFARCTION; METABOLIC SYNDROME; CARDIOVASCULAR-DISEASE; RANCHO BERNARDO; RISK; RESISTANCE; MORTALITY; LIVER; HEART;
D O I：
10.3109/1354750X.2012.762806
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Objective: To clarify the correlation between serum fetuin-A levels and the presence and severity of coronary artery disease (CAD) in patients with type 2 diabetes (T2DM). Methods: A total of 241 consecutive patients with T2DM and 69 controls were recruited. Serum fetuin-A levels were analyzed by enzyme-linked immunosorbent assay. The presence and severity of CAD were evaluated by coronary angiography (CAG). Results: Serum fetuin-A levels are independently correlated with the presence and severity of CAD in T2DM patients. Conclusions: Fetuin-A might serve as a potential biomarker for reflecting the development and progression of CAD in T2DM patients.
引用
收藏
页码：160 / 164
页数：5
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