Serum fetuin-A levels are associated with the presence and severity of coronary artery disease in patients with type 2 diabetes

被引：43

作者：

Zhao, Zi-Wen ^{[1
]}

Lin, Chao-Gui ^{[1
]}

Wu, Ling-Zhen ^{[1
]}

Luo, Yu-Kun ^{[1
]}

Fan, Lin ^{[1
]}

Dong, Xian-feng ^{[1
]}

Zheng, Hong ^{[1
]}

机构：

[1] Fujian Med Univ, Fujian Inst Coronary Artery Dis, Union Hosp, Dept Cardiol, Fuzhou 350001, Peoples R China

来源：

BIOMARKERS | 2013年 / 18卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Biomarker; coronary artery disease; diabetes; fetuin-A; MYOCARDIAL-INFARCTION; METABOLIC SYNDROME; CARDIOVASCULAR-DISEASE; RANCHO BERNARDO; RISK; RESISTANCE; MORTALITY; LIVER; HEART;

D O I：

10.3109/1354750X.2012.762806

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Objective: To clarify the correlation between serum fetuin-A levels and the presence and severity of coronary artery disease (CAD) in patients with type 2 diabetes (T2DM). Methods: A total of 241 consecutive patients with T2DM and 69 controls were recruited. Serum fetuin-A levels were analyzed by enzyme-linked immunosorbent assay. The presence and severity of CAD were evaluated by coronary angiography (CAG). Results: Serum fetuin-A levels are independently correlated with the presence and severity of CAD in T2DM patients. Conclusions: Fetuin-A might serve as a potential biomarker for reflecting the development and progression of CAD in T2DM patients.

引用

页码：160 / 164

页数：5

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