A self-cleaving DNA nucleoside

被引:6
|
作者
Gupta, V [1 ]
Kool, ET [1 ]
机构
[1] UNIV ROCHESTER, DEPT CHEM, ROCHESTER, NY 14627 USA
关键词
D O I
10.1039/a700626h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
An allyl-modified nucleoside has been shown to self-alkylate and depurinate on treatment with iodine and heat; placement in DNA strands yields site-directed cleavage of the DNA.
引用
收藏
页码:1425 / 1426
页数:2
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