A self-cleaving DNA nucleoside

被引：6
|
作者：
Gupta, V [1 ]
Kool, ET [1 ]
机构：
[1] UNIV ROCHESTER, DEPT CHEM, ROCHESTER, NY 14627 USA
来源：
CHEMICAL COMMUNICATIONS | 1997年 / 15期
关键词：
D O I：
10.1039/a700626h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An allyl-modified nucleoside has been shown to self-alkylate and depurinate on treatment with iodine and heat; placement in DNA strands yields site-directed cleavage of the DNA.
引用
收藏
页码：1425 / 1426
页数：2
相关论文
共 50 条
  • [21] A genetic system yields self-cleaving inteins for bioseparations
    Wood, DW
    Wu, W
    Belfort, G
    Derbyshire, V
    Belfort, M
    NATURE BIOTECHNOLOGY, 1999, 17 (09) : 889 - 892
  • [22] Autoprotease Npro: Analysis of self-cleaving fusion protein
    Wellhoefer, Martin
    Sprinzl, Wolfgang
    Hahn, Rainer
    Jungbauer, Alois
    JOURNAL OF CHROMATOGRAPHY A, 2013, 1304 : 92 - 100
  • [23] Scaling Catalytic Contributions of Small Self-Cleaving Ribozymes
    Egger, Michaela
    Bereiter, Raphael
    Mair, Stefan
    Micura, Ronald
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 61 (41)
  • [24] Self-cleaving ribozymes of hepatitis delta virus RNA
    Been, MD
    Wickham, GS
    EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 247 (03): : 741 - 753
  • [25] A widespread self-cleaving ribozyme class is revealed by bioinformatics
    Roth, Adam
    Weinberg, Zasha
    Chen, Andy G. Y.
    Kim, Peter B.
    Ames, Tyler D.
    Breaker, Ronald R.
    NATURE CHEMICAL BIOLOGY, 2014, 10 (01) : 56 - U92
  • [26] Imidazole rescue of a cytosine mutation in a self-cleaving ribozyme
    Perrotta, AT
    Shih, IH
    Been, MD
    SCIENCE, 1999, 286 (5437) : 123 - 126
  • [27] A widespread self-cleaving ribozyme class is revealed by bioinformatics
    Roth A.
    Weinberg Z.
    Chen A.G.Y.
    Kim P.B.
    Ames T.D.
    Breaker R.R.
    Nature Chemical Biology, 2014, 10 (1) : 56 - 60
  • [28] Crystal structure of Pistol, a class of self-cleaving ribozyme
    Nguyen, Laura A.
    Wang, Jimin
    Steitz, Thomas A.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (05) : 1021 - 1026
  • [29] A genetic system yields self-cleaving inteins for bioseparations
    David W. Wood
    Wei Wu
    Georges Belfort
    Victoria Derbyshire
    Marlene Belfort
    Nature Biotechnology, 1999, 17 : 889 - 892
  • [30] Self-cleaving fusion tags for recombinant protein production
    Yifeng Li
    Biotechnology Letters, 2011, 33 : 869 - 881
12345