Intestinal Spirochetosis mimicking inflammatory bowel disease in children

被引：14

作者：

Helbling, Rossana ^{[1
]}

Osterheld, Maria-Chiara ^{[2
]}

Vaudaux, Bernard ^{[3
]}

Jaton, Katia ^{[4
]}

Nydegger, Andreas ^{[1
]}

机构：

[1] Univ Lausanne, CHU Vaudois, Dept Pediat, Pediat Gastroenterol Unit, CH-1011 Lausanne, Switzerland

[2] Univ Lausanne, CHU Vaudois, Inst Pathol, CH-1011 Lausanne, Switzerland

[3] Univ Lausanne, CHU Vaudois, Pediat Infect Dis Unit, Dept Pediat, CH-1011 Lausanne, Switzerland

[4] Univ Lausanne, CHU Vaudois, Inst Microbiol, CH-1011 Lausanne, Switzerland

来源：

BMC PEDIATRICS | 2012年 / 12卷

关键词：

Intestinal spirochetosis; Brachyspira aalborgi; Brachyspira pilosicoli; Inflammatory bowel disease; CLINICAL-SIGNIFICANCE; BRACHYSPIRA-AALBORGI; COLORECTAL SPIROCHETOSIS; PILOSICOLI; INFECTION; FEATURES; AGENTS;

D O I：

10.1186/1471-2431-12-163

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Background: Intestinal spirochetosis is an unusual infection in children and its clinical significance in humans is uncertain. The presence of these microorganisms in humans is well-known since the late 1800's and was first described in 1967 by Harland and Lee by electron microscopy. Case presentation: This article reports the findings of one pediatric case, review of the current literature, and an overview of therapeutic options. Conclusion: A high degree of suspicion is required in cases presenting with abdominal pain, chronic diarrhoea and/or hematochezia associated with a normal endoscopic examination, thus emphasizing the importance of multiple biopsies throughout the colon.

引用

页数：6

共 29 条

[1]

Alsaigh N, 2002, Colorectal Dis, V4, P97, DOI 10.1046/j.1463-1318.2002.00284.x

[2] INTESTINAL SPIROCHETOSIS - AN ELECTRON-MICROSCOPIC STUDY OF AN UNUSUAL CASE [J].

ANTONAKOPOULOS, G ;

NEWMAN, J ;

WILKINSON, M .

HISTOPATHOLOGY, 1982, 6 (04) :477-488

[3] Brachyspira pilosicoli bloodstream infections: Case report and review of the literature [J].

Bait-Merabet L. ;

Thille A. ;

Legrand P. ;

Brun-Buisson C. ;

Cattoir V. .

Annals of Clinical Microbiology and Antimicrobials, 7 (1)

[4] In vitro antimicrobial susceptibility of Brachyspira pilosicoli isolates from humans [J].

Brooke, CJ ;

Hampson, DJ ;

Riley, TV .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (07) :2354-2357

[5] Nomenclature for aerobic and facultative bacteria [J].

Bruckner, DA ;

Colonna, P .

CLINICAL INFECTIOUS DISEASES, 1997, 25 (01) :1-10

[6] Infective colitis associated with human intestinal spirochetosis [J].

Calderaro, Adriana ;

Bommezzadri, Simona ;

Gorrini, Chiara ;

Piccolo, Giovanna ;

Peruzzi, Simona ;

Villanacci, Vincenzo ;

Zambelli, Claudia ;

Dettori, Giuseppe ;

Chezzi, Carlo .

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2007, 22 (11) :1772-1779

[7] Occurrence of human intestinal spirochetosis in comparison with infections by other enteropathogenic agents in an area of the Northern Italy [J].

Calderaro, Adriana ;

Gorrini, Chiara ;

Peruzzi, Simona ;

Piccolo, Giovanna ;

Dettori, Giuseppe ;

Chezzi, Carlo .

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2007, 59 (02) :157-163

[8] Intestinal Spirochetosis in Children: Five New Cases and a 20-Year Review of the Literature [J].

Carpentieri, David F. ;

Souza-Morones, Stephanie ;

Gardetto, Jennifer S. ;

Ross, Hillary M. ;

Downey, Katherine ;

Ingebo, Kristy ;

Siaw, Emmanuel .

PEDIATRIC AND DEVELOPMENTAL PATHOLOGY, 2010, 13 (06) :471-475

[9] The Histological Features of Intestinal Spirochetosis in a Series of 113 Patients [J].

Carr, Norman J. ;

Mahajan, Hema ;

Tan, King L. ;

Sharma, Raghwa .

INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY, 2010, 18 (02) :144-148

[10]

da Cunha Ferreira R M, 1993, J Pediatr Gastroenterol Nutr, V17, P333, DOI 10.1097/00005176-199310000-00020

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