Drug-eluting stents

被引：0

作者：

Ma, Xiaodong ^{[1
,2
]}

Wu, Tim ^{[1
,2
]}

Robich, Michael P. ^{[3
]}

Wang, Xingwei ^{[1
]}

Wu, Hao ^{[2
]}

Buchholz, Bryan ^{[1
]}

McCarthy, Stephen ^{[1
]}

机构：

[1] Univ Massachusetts, Biomed Engn & Biotechnol Doctoral Program, Lowell, MA 01854 USA

[2] VasoTech Inc, Lowell, MA 01854 USA

[3] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Surg,Div Cardiothorac Surg, Boston, MA 02215 USA

来源：

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2010年 / 3卷 / 03期

基金：

美国国家卫生研究院;

关键词：

Drug-eluting stents; restenosis; thrombosis;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Coronary artery disease (CAD) is currently a leading cause of death worldwide. Drug-eluting stents (DESs) have been dominant for the treatment of CAD in the interventional cardiology world owing to their efficacy in significantly reducing restenosis. However, late stage stent thrombosis has become a major concern. Stent platform, drug delivery vehicle and type of drug are three parts of DES and each part affects the performance of the DES. Aiming to provide a clue for the design of future DES, this review focuses on the development of the three major components of DES and their roles in restenosis and thrombosis.

引用

页码：192 / 201

页数：10

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