Toll-Like Receptor Expression Pattern: Clinical Application

被引：3
|
作者：
Moossavi, Shirin [5 ]
Rezaei, Nima [1 ,2 ,3 ,4 ]
机构：
[1] Childrens Med Ctr Hosp, Tehran 14194, Iran
[2] Univ Sheffield, Sch Med & Biomed Sci, Dept Infect & Immun, Sheffield, S Yorkshire, England
[3] Univ Tehran Med Sci, Sch Med, Dept Immunol, Mol Immunol Res Ctr, Tehran, Iran
[4] Univ Tehran Med Sci, Childrens Med Ctr, Res Ctr Immunodeficiencies, PediatricsCtr Excellence, Tehran, Iran
[5] Univ Tehran Med Sci, Digest Dis Res Ctr, Tehran, Iran
来源：
JOURNAL OF CLINICAL IMMUNOLOGY | 2012年 / 32卷 / 06期
关键词：
Toll-like receptor; expression pattern; COLORECTAL-CANCER; MICROENVIRONMENT; TUMORS;
D O I：
10.1007/s10875-012-9719-7
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We read with interest the recent paper in the JoCI, entitled 'Study of the expression of Toll-Like Receptors in Different Histological Types of Colorectal Polyps and Their Relationship with Colorectal Cancer' by Eir et al. TLR7 and 9 expression is altered in CRC vs. normal control; which is proposed to be correlated with adenomacarcinoma progression. The fact that other TLRs were not observed to be differentially expressed is in contrast with published reports; which could be explained by the limitations of the employed method and disregarding the spatiotemporal variation in TLR expression pattern.
引用
收藏
页码：1421 / 1422
页数：2
相关论文
共 50 条
  • [31] Responsiveness of intestinal epithelial cell lines to lipopolysaccharide is correlated with Toll-like receptor 4 but not Toll-like receptor 2 or CD14 expression
    Böcker, U
    Yezerskyy, O
    Feick, P
    Manigold, T
    Panja, A
    Kalina, U
    Herweck, F
    Rossol, S
    Singer, MV
    INTERNATIONAL JOURNAL OF COLORECTAL DISEASE, 2003, 18 (01) : 25 - 32
  • [32] Bacterial Modulation of Human Fetal Membrane Toll-like Receptor Expression
    Abrahams, Vikki M.
    Potter, Julie A.
    Bhat, Geeta
    Peltier, Morgan R.
    Saade, George
    Menon, Ramkumar
    AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2013, 69 (01) : 33 - 40
  • [33] Polymorphisms in vitamin D receptor, toll-like receptor 2 and Toll-Like receptor 4 genes links with Dengue susceptibility
    Singh, Arvind Kumar
    Prakash, Shantanu
    Garg, R. K.
    Jain, Parul
    Kumar, Rashmi
    Jain, Amita
    BIOINFORMATION, 2021, 17 (04) : 506 - 513
  • [34] Administration of a dual toll-like receptor 7 and toll-like receptor 8 agonist protects against influenza in rats
    Hammerbeck, David M.
    Burleson, Gary R.
    Schuller, Craig J.
    Vasilakos, John P.
    Tomai, Mark
    Egging, Elaine
    Cochran, Felicia R.
    Woulfe, Susan
    Miller, Richard L.
    ANTIVIRAL RESEARCH, 2007, 73 (01) : 1 - 11
  • [35] TOLL-LIKE RECEPTOR SIGNALING PATHWAYS AND THE EVIDENCE LINKING TOLL-LIKE RECEPTOR SIGNALING TO CARDIAC ISCHEMIA/REPERFUSION INJURY
    Wang, Yue
    Abarbanell, Aaron M.
    Herrmann, Jeremy L.
    Weil, Brent R.
    Poynter, Jeffrey
    Manukyan, Mariuxi C.
    Crisostomo, Paul R.
    Meldrum, Daniel R.
    SHOCK, 2010, 34 (06): : 548 - 557
  • [36] Studies on expression pattern of toll-like receptor 5 (TLR5) in Edwardsiella tarda infected Pangasianodon hypophthalmus
    Jayaramu, Poojashree Kachigere
    Tripathi, Gayatri
    Kumar, A. Pavan
    Keezhedath, Jeena
    Pathan, Mujahid Khan
    Kurcheti, Pani Prasad
    FISH & SHELLFISH IMMUNOLOGY, 2017, 63 : 68 - 73
  • [37] Cooperative Interactions between Toll-Like Receptor 2 and Toll-Like Receptor 4 in Murine Klebsiella pneumoniae Infections
    Jeon, Hee-Yeon
    Park, Jong-Hyung
    Park, Jin-Il
    Kim, Jun-Young
    Seo, Sun-Min
    Ham, Seung-Hoon
    Jeong, Eui-Suk
    Choi, Yang-Kyu
    JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, 2017, 27 (08) : 1529 - 1538
  • [38] Toll-like receptor activation and expression in bovine alpha-herpesvirus infections
    Marin, M. S.
    Quintana, S.
    Faverin, C.
    Leunda, M. R.
    Odeon, A. C.
    Perez, S. E.
    RESEARCH IN VETERINARY SCIENCE, 2014, 96 (01) : 196 - 203
  • [39] Toll-like receptor agonists in cancer therapy
    Adams, Sylvia
    IMMUNOTHERAPY, 2009, 1 (06) : 949 - 964
  • [40] Toll-like receptor alterations in myelodysplastic syndrome
    Y Wei
    S Dimicoli
    C Bueso-Ramos
    R Chen
    H Yang
    D Neuberg
    S Pierce
    Y Jia
    H Zheng
    H Wang
    X Wang
    M Nguyen
    S A Wang
    B Ebert
    R Bejar
    R Levine
    O Abdel-Wahab
    M Kleppe
    I Ganan-Gomez
    H Kantarjian
    G Garcia-Manero
    Leukemia, 2013, 27 : 1832 - 1840
12345