Serum (1→3)-β-D-Glucan Measurement in Coccidioidomycosis

被引：41
|
作者：
Thompson, George R., III [1 ,2 ]
Bays, Derek J. [1 ]
Johnson, Suzanne M. [1 ]
Cohen, Stuart H. [2 ]
Pappagianis, Demosthenes [1 ]
Finkelman, Malcolm A. [3 ]
机构：
[1] Univ Calif Davis, Dept Med Microbiol & Immunol, Coccidioidomycosis Serol Lab, Davis, CA 95616 USA
[2] Univ Calif Davis, Med Ctr, Dept Internal Med, Div Infect Dis, Sacramento, CA 95817 USA
[3] Associates Cape Cod Inc, E Falmouth, MA USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 09期
关键词：
INVASIVE FUNGAL-INFECTIONS; SURVEILLANCE NETWORK TRANSNET; BETA-D-GLUCAN; TRANSPLANT RECIPIENTS; DIAGNOSIS; POSADASII; LEUKEMIA; MYCOSIS;
D O I：
10.1128/JCM.00631-12
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The serum (1 -> 3)-beta-D-glucan assay has emerged as an important diagnostic test for invasive fungal disease. The utility of this assay in coccidioidomycosis has not been previously studied. Using a cutoff value of >= 80 pg/ml, we found the sensitivity (43.9%), specificity (91.1%), positive predictive value (81.8%), and negative predictive value (64.1%) to be similar to those of the assay in diagnosing other invasive mycoses.
引用
收藏
页码：3060 / 3062
页数：3
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