An application of GafChromic MD-55 film for 67.5 MeV clinical proton beam dosimetry

被引:32
作者
Daftari, I
Castenadas, C
Petti, PL
Singh, RP
Verhey, LJ
机构
[1] Univ Calif San Francisco, Dept Radiat Oncol, San Francisco, CA 94143 USA
[2] Univ Calif Davis, Crocker Nucl Lab, Davis, CA 95616 USA
[3] Univ Calif Berkeley, Lawrence Berkeley Lab, Berkeley, CA 94720 USA
关键词
D O I
10.1088/0031-9155/44/11/304
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The purpose of this study is to explore the use of GafChromic MD-55 (RC) film for 67.5 MeV clinical proton beam dosimetry at the Crocker Nuclear Laboratory, University of California, Davis. Several strips of RC film 6 cm x 6 cm in dimension were irradiated at a depth of 18.2 mm corresponding to the middle of a 24 mm spread-out Bragg peak (SOBP). The films were irradiated to a proton dose in the range of 0.5 Gy to 100 Gy. The beam profiles were also measured at the middle of the 24 mm SOBP. The Bragg peak was measured by using a wedge shaped phantom made of Lucite. The Bragg peak measured with RC film was compared with diode and ionization chamber measurements. After background subtraction, the calibration of the dose response of RC film showed, to a maximum deviation of 10%, a linear increase of optical density (OD) with dose from 0.5 to 100 Gy. The uniformity of OD over a single sheet of film showed a variation of +/-6%. The distal-fall off between 90% and 20% measured with GafChromic film for the Bragg peak was 1.3 mm as compared to 1.1 mm for a diode measurement and 1.4 mm for an ionization chamber measurement. The FWHM of the Bragg peak was 7.5 mm when measured with GafChromic film, 5.3 mm when measured with a diode and 8.1 mm as measured by an ionization chamber. The peak/plateau ratio with GafChromic film was 3.3 as compared to 3.7 with a diode and 3.2 with an ionization chamber. In conclusion, GafChromic MD-55 film may be a useful and convenient detector for dose measurement and quality assurance programmes of proton beams.
引用
收藏
页码:2735 / 2745
页数:11
相关论文
共 27 条
[1]   Fast 2D phantom dosimetry for scanning proton beams [J].
Boon, SN ;
van Luijk, P ;
Schippers, JM ;
Meertens, H ;
Denis, JM ;
Vynckier, S ;
Medin, J ;
Grusell, E .
MEDICAL PHYSICS, 1998, 25 (04) :464-475
[2]  
BRASSART N, 1996, PTCOG M PSI SWITZ 19, P16
[3]   Comments on "Quantitative evaluation of radiochromic firm response for two-dimensional dosimetry" [Med. Phys. 24, 223-231 (1997)] [J].
Butson, M ;
Yu, PKN .
MEDICAL PHYSICS, 1998, 25 (05) :793-793
[4]  
CHU RDH, 1990, RADIAT PHYS CHEM, V35, P767
[5]   New UCSF proton ocular beam facility at the Crocker Nuclear Laboratory Cyclotron (UC Davis) [J].
Daftari, IK ;
Renner, TR ;
Verhey, LJ ;
Singh, RP ;
Nyman, M ;
Petti, PL ;
Castro, JR .
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1996, 380 (03) :597-612
[6]  
*INT COMM RAD UN M, 1998, ICRU59 INT COMM RA 1
[7]  
*INT EL COMM, 1984, 35I IEC
[8]  
*INT EL COMM, 1984, 35II IEC
[9]   GafChromic MD-55: Investigated as a precision dosimeter [J].
Klassen, NV ;
van der Zwan, L ;
Cygler, J .
MEDICAL PHYSICS, 1997, 24 (12) :1924-1934
[10]   NMR RELAXATION ENHANCEMENT IN GELS POLYMERIZED AND CROSS-LINKED BY IONIZING-RADIATION - A NEW APPROACH TO 3D DOSIMETRY BY MRI [J].
MARYANSKI, MJ ;
GORE, JC ;
KENNAN, RP ;
SCHULZ, RJ .
MAGNETIC RESONANCE IMAGING, 1993, 11 (02) :253-258